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Open AccessJournal ArticleDOI

Antibiotic growth promoters in agriculture: history and mode of action

Julia J. Dibner, +1 more
- 01 Apr 2005 - 
- Vol. 84, Iss: 4, pp 634-643
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TLDR
The biological basis for antibiotic effects on animal growth efficiency will consider effects on intestinal microbiota and effects on the host animal and will use the germ-free animal to illustrate effects of the conventional microflora.
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This article is published in Poultry Science.The article was published on 2005-04-01 and is currently open access. It has received 1239 citations till now. The article focuses on the topics: European union.

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Citations
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Food Animals and Antimicrobials: Impacts on Human Health

TL;DR: The substantial and expanding volume of evidence reporting animal-to-human spread of resistant bacteria, including that arising from use of NTAs, supports eliminating NTA use in order to reduce the growing environmental load of resistance genes.
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Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential

TL;DR: Their broad spectrum of activity, non-specific mode of action and safety makes them attractive as antibacterial agents for various applications in medicine, agriculture and food preservation, especially where the use of conventional antibiotics is undesirable or prohibited.
Journal ArticleDOI

History of the Use of Antibiotic as Growth Promoters in European Poultry Feeds

TL;DR: The European support to recommendations of the World Health Organization, the Food and Agriculture Organization, and the World Organization for Animal Health for a ban on antimicrobial use in animal feeds is expected to favor other countries also phase out these substances out.
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Review of antibiotic resistance in China and its environment

TL;DR: It is important to understand the current state of antibiotic use in China and its relationship to ARG prevalence and diversity in the environment, and also future needs in mitigating the spread of antibiotic resistance in the environments, particularly under the 'planetary health' perspective.
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In-feed antibiotic effects on the swine intestinal microbiome.

TL;DR: Analysis of the metagenomes showed that microbial functional genes relating to energy production and conversion were increased in the antibiotic-fed pigs and that antibiotic resistance genes increased in abundance and diversity in the medicated swine microbiome despite a high background of resistance genes in nonmedication swine.
References
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Journal ArticleDOI

Microbial ecology of the gastrointestinal tract

TL;DR: A comparison study of how microbes in the BIOTA make their living (NICHES) and the localization of climax communities in adults reveals a complex web of interactions between the host organism and the environment.
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Developmental microbial ecology of the neonatal gastrointestinal tract

TL;DR: In this review, the development of the intestinal microbiota is discussed in terms of initial acquisition and subsequent succession of bacteria in human infants and the advantages of modern molecular ecology techniques that provide sensitive and specific, culture-independent evaluation of the gastrointestinal ecosystem are introduced.
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Human fecal flora: the normal flora of 20 Japanese-Hawaiians.

TL;DR: Quantitative and qualitative examination of the fecal flora of 20 clinically healthy Japanese-Hawaiian males was carried out by using anaerobic tube culture techniques, and differential characteristics of previously unreported species are presented.
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Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data

TL;DR: The application of the 'precautionary principle' is a non-scientific approach that assumes that risk assessments will be carried out, and anti-Gram-positive growth promoters would be expected to have little effect on most Gram-negative organisms.
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Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.

TL;DR: Germ-free mice contaminated with the intestinal flora of an antibiotic-treated animal and their offspring housed in a germ-free isolator showed high values of CR, and apparently, these anaerobes are responsible for CR in these and in conventional mice.
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