Institution
University of Alberta Hospital
Healthcare•Edmonton, Alberta, Canada•
About: University of Alberta Hospital is a healthcare organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 1798 authors who have published 1906 publications receiving 54928 citations.
Papers published on a yearly basis
Papers
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Paris Diderot University1, Peter MacCallum Cancer Centre2, Wrocław Medical University3, Medical University of Łódź4, Samsung Medical Center5, National Health Service6, Princess Margaret Cancer Centre7, Centre Hospitalier Universitaire de Toulouse8, University of Alberta Hospital9, Spanish National Research Council10, Harvard University11, Celgene12
TL;DR: Univariate analysis showed favorable trends for azacitidine compared with CCR across all subgroups defined by baseline demographic and disease features, and adverse events were consistent with the well-established safety profile of azacItidine.
902 citations
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TL;DR: This review supports the presence of significant differences between schizophrenic males and females arising from the interplay of sex hormones, neurodevelopmental and psychosocial sex differences.
Abstract: Objective: To comprehensively and critically review the literature on gender differences in schizophrenia.
Method: An initial search of MEDLINE abstracts (1966–1999) was conducted using the terms sex or gender and schizophrenia, followed by systematic search of all relevant articles.
Results: Males have consistently an earlier onset, poorer premorbid functioning and different premorbid behavioral predictors. Males show more negative symptoms and cognitive deficits, with greater structural brain and neurophysiological abnormalities. Females display more affective symptoms, auditory hallucinations and persecutory delusions with more rapid and greater responsivity to antipsychotics in the pre-menopausal period but increased side effects. Course of illness is more favorable in females in the short- and middle-term, with less smoking and substance abuse. Families of males are more critical, and expressed emotion has a greater negative impact on males. There are no clear sex differences in family history, obstetric complications, minor physical anomalies and neurological soft signs.
Conclusion: This review supports the presence of significant differences between schizophrenic males and females arising from the interplay of sex hormones, neurodevelopmental and psychosocial sex differences.
743 citations
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TL;DR: As new drugs are developed, it is suggested that the assessment processes should include both surrogate endpoints and clinical outcomes, so that patients and their physicians can be confident that the putative benefits of such drugs outweigh their risks and costs.
718 citations
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Johns Hopkins University1, Paris Descartes University2, University of Barcelona3, University of Colorado Denver4, University of Pennsylvania5, University of Chicago6, University of Alberta Hospital7, University of Cambridge8, Vanderbilt University Medical Center9, Stanford University10, University of Giessen11, Virginia Commonwealth University12, University of California, San Diego13, University of Paris-Sud14
TL;DR: An overview of specific inflammatory pathways involving cells, chemokines and cytokines, cellular dysfunctions, growth factors, and viral proteins is provided, highlighting their potential role in pulmonary vascular remodeling and the possibility of future targeted therapy.
646 citations
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TL;DR: Sarcopenia is associated with mortality in patients with cirrhosis and does not correlate with the degree of liver dysfunction evaluated by using conventional scoring systems, but scoring systems should include evaluation of sarcopenia to better assess mortality among patients with Cirrhosis.
602 citations
Authors
Showing all 1805 results
Name | H-index | Papers | Citations |
---|---|---|---|
Han Zhang | 130 | 970 | 58863 |
Marcello Tonelli | 128 | 701 | 115576 |
Sharon E. Straus | 120 | 879 | 72513 |
Paul W. Armstrong | 114 | 811 | 79389 |
Finlay A. McAlister | 94 | 530 | 34810 |
Stephen L. Archer | 93 | 348 | 36490 |
Brian H. Rowe | 91 | 618 | 31205 |
Thomas J. Marrie | 87 | 389 | 35800 |
Tongwen Chen | 85 | 519 | 26307 |
David Feeny | 81 | 338 | 33500 |
Sumit R. Majumdar | 80 | 394 | 24718 |
Richard N. Fedorak | 78 | 405 | 29843 |
Gavin Y. Oudit | 74 | 327 | 19506 |
Jason R.B. Dyck | 73 | 285 | 19123 |
Evangelos D. Michelakis | 72 | 174 | 18755 |