University of Hawaii

About: University of Hawaii is a education organization based out in Honolulu, Hawaii, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 17971 authors who have published 36102 publications receiving 1620196 citations.

Working abroad, working with others: How firms learn to operate international joint ventures

Abstract: textSuccessful international joint ventures entail both learning to operate across national boundaries and learning to cooperate. Hypotheses grounded in organizational learning theory were tested with event-history analysis and data on 1,493 expansions of 25 large Dutch firms between 1966 and 1994. Experience with domestic joint ventures and with international wholly owned subsidiaries contributed to the longevity of international joint ventures, but prior experience with international joint ventures did not.

Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication

Abstract: Phorbol esters (e.g., TPA) activate protein kinase C (PKC), increase connexin43 (Cx43) phosphorylation, and decrease cell–cell communication via gap junctions in many cell types. We asked whether PKC directly phosphorylates and regulates Cx43. Rat epithelial T51B cells metabolically labeled with 32Pi yielded two-dimensional phosphotryptic maps of Cx43 with several phosphopeptides that increased in intensity upon TPA treatment. One of these peptides comigrated with the major phosphopeptide observed after PKC phosphorylation of immunoaffinity-purified Cx43. Purification of this comigrating peptide and subsequent sequencing indicated that the phosphorylated serine was residue 368. To pursue the functional importance of phosphorylation at this site, fibroblasts from Cx43−/− mice were transfected with either wild-type (Cx43wt) or mutant Cx43 (Cx43-S368A). Intercellular dye transfer studies revealed different responses to TPA and were followed by single channel analyses. TPA stimulation of T51B cells or Cx43wt-transfected fibroblasts caused a large increase in the relative frequency of ∼50-pS channel events and a concomitant loss of ∼100-pS channel events. This change to ∼50-pS events was absent when cells transfected with Cx43-S368A were treated with TPA. These data strongly suggest that PKC directly phosphorylates Cx43 on S368 in vivo, which results in a change in single channel behavior that contributes to a decrease in intercellular communication.

DarkSide-20k: A 20 tonne two-phase LAr TPC for direct dark matter detection at LNGS

Abstract: Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant 39Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of $>3 \times 10^{9}$ is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than $< 0.1$ events (other than $ u$ -induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured in situ, giving sensitivity to WIMP-nucleon cross sections of $1.2 \times 10^{-47}$ cm2 ( $1.1 \times 10^{-46}$ cm2) for WIMPs of 1 TeV/c2 (10 TeV/c2) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.

SPITZER QUASAR AND ULIRG EVOLUTION STUDY (QUEST). IV. COMPARISON OF 1 Jy ULTRALUMINOUS INFRARED GALAXIES WITH PALOMAR-GREEN QUASARS

Abstract: We report the results from a comprehensive study of 74 ultraluminous infrared galaxies (ULIRGs) and 34 Palomar-Green (PG) quasars within z ~ 0.3 observed with the Spitzer Infrared Spectrograph (IRS). The contribution of nuclear activity to the bolometric luminosity in these systems is quantified using six independent methods that span a range in wavelength and give consistent results within ~±10%-15% on average. This agreement suggests that deeply buried active galactic nuclei (AGNs) invisible to Spitzer IRS but bright in the far-infrared are not common in this sample. The average derived AGN contribution in ULIRGs is ~35%-40%, ranging from ~15%-35% among "cool" (f_(25)/f_(60) ≤ 0.2) optically classified H II-like and LINER ULIRGs to ~50 and ~75% among warm Seyfert 2 and Seyfert 1 ULIRGs, respectively. This number exceeds ~80% in PG QSOs. ULIRGs fall in one of three distinct AGN classes: (1) objects with small extinctions and large polycyclic aromatic hydrocarbon (PAH) equivalent widths are highly starburst-dominated; (2) systems with large extinctions and modest PAH equivalent widths have larger AGN contributions, but still tend to be starburst-dominated; and (3) ULIRGs with both small extinctions and small PAH equivalent widths host AGN that are at least as powerful as the starbursts. The AGN contributions in class 2 ULIRGs are more uncertain than in the other objects, and we cannot formally rule out the possibility that these objects represent a physically distinct type of ULIRGs. A morphological trend is seen along the sequence (1)-(2)-(3), in general agreement with the standard ULIRG–QSO evolution scenario and suggestive of a broad peak in extinction during the intermediate stages of merger evolution. However, the scatter in this sequence, including the presence of a significant number of AGN-dominated systems prior to coalescence and starburst-dominated but fully merged systems, implies that black hole accretion, in addition to depending on the merger phase, also has a strong chaotic/random component, as in local AGNs.

Synoptic climatology of transient tropical intraseasonal convection anomalies: 1975?1985

Abstract: Pentad mean anomaly maps were used to study the climatology of tropical intraseasonal convection anomaly (TICA) as a dynamic system. One hundred and twenty-two events were identified and classified into three categories: eastward (77), independent northward (27), and westward (18) propagation. The eastward propagation is more active in boreal winter than in summer, while the independent northward propagation, which is not associated with equatorial eastward propagation, occurs in boreal summer from May to October. The eastward moving TICA exhibits three major paths: 1) eastward along the equator from Africa to the mid-Pacific, 2) first eastward along the equator, then either turning north-east to the northwest Pacific or turning southeast to the southwest Pacific at the maritime continent, and 3) the main anomaly moves eastward along the equator with split center(s) moving northward over the Indian and/or western Pacific Oceans. The equatorial Indian Ocean and the western Pacific intertropical convergence zone are preferred geographic locations for their development, while the maritime continent and central Pacific are regions of dissipation. Independent northward propagation is confined to the Indian and western Pacific monsoon regions. Its existence suggests that the mechanism responsible for meridional propagation may differ from that for eastward propagation. The dynamic effect of the equator and the thermodynamic effect of the underlying warm ocean water are basic factors in trapping TICA in the deep tropics, while the annual march of maximum SST (thermal equator) and the monsoon circulation have profound influences on the annual variation and meridional movement of TICA.