Institution
VU University Medical Center
Healthcare•Amsterdam, Noord-Holland, Netherlands•
About: VU University Medical Center is a healthcare organization based out in Amsterdam, Noord-Holland, Netherlands. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 10882 authors who have published 22907 publications receiving 1156378 citations. The organization is also known as: VUmc.
Topics: Population, Randomized controlled trial, Cancer, Anxiety, Dementia
Papers published on a yearly basis
Papers
More filters
••
Brigham and Women's Hospital1, Houston Methodist Hospital2, Mount Sinai Hospital3, Henry Ford Hospital4, University of Pittsburgh5, National Institutes of Health6, Mayo Clinic7, City of Hope National Medical Center8, Queen's University9, VU University Medical Center10, Memorial Sloan Kettering Cancer Center11
TL;DR: 37 guideline items address 14 subjects, including 15 recommendations (evidence grade A/B), to use testing for EGFR mutations and ALK fusions to guide patient selection for therapy with an epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK) inhibitor in all patients with advanced-stage lung cancer.
483 citations
••
TL;DR: There is a great need for additional high quality trials before any conclusions on effectiveness of bio-behavioural interventions for reduction of neck and upper limb problems and return to work after these symptoms can be made.
Abstract: Work related neck and upper limb symptoms have a multi-factorial origin Possible risk factors are of a physical, psychosocial or personal origin These factors can reinforce each other and their influence can also be mediated by cultural or societal factors Initially, most research on neck and upper limb symptoms focused on work-related physical exposure Nowadays, psychosocial work characteristics are recognized as important risk factors Various models have been developed to offer frameworks for possible pathways, but their empirical support is still not conclusive In part I of this paper an overview is presented of the results of recent epidemiological studies on work related psychosocial and personal risk factors for neck and upper limb symptoms In addition, the interplay between these factors and the possible intermediate role of an individuals work style in this process is explored In contrast to previous reviews, it is now possible to base the conclusions on the effect of work related psychosocial factors on neck and upper limb symptoms on quite a few longitudinal studies These studies show that high work demands or little control at work are often related to these symptoms However, this relationship is neither very strong nor very specific Perceived stress is studied in not as many studies but more consistently related to neck and upper limb symptoms This also applies to general distress or other pain (co-morbidity) Job dissatisfaction does not contribute to neck and upper limb symptoms Too little research on personal characteristics is available to draw any conclusions It is plausible that behavioural aspects, such as work style, are of importance in the etiology of work related upper limb symptoms However, studies concerning these factors are promising but too scarce to draw conclusions Future studies should address these behavioural aspects In part II, the recent studies on the effectiveness of preventive measures for work related neck and upper limb problems are discussed Few randomised or non randomised controlled trials have been carried out to evaluate the effectiveness of individual or organisational interventions to improve work related psychosocial factors Very few have reported on the preventive effect for work related neck and upper limb symptoms Therefore, there is a great need for additional high quality trials before any conclusions on effectiveness of bio-behavioural interventions for reduction of neck and upper limb problems and return to work after these symptoms can be made From the low back pain intervention research can be learned that interventions should best be targeted to both the worker and the organisation and that interventions will only be successful when all stakeholders are involved
483 citations
••
TL;DR: This review highlights key cell biological processes that couple exosome biogenesis to cargo sorting in cancer cells and discusses how the bidirectional communication between tumor and non-malignant cells affect cancer growth and metastatic behavior.
481 citations
••
TL;DR: This review gives an overview of modern network theory and its applications to healthy brain function and neurological disease, in particular using techniques from clinical neurophysiology, such as EEG and MEG.
481 citations
••
TL;DR: The LAPAQ appears to be a valid and reliable instrument for classifying physical activity in older people and was easier to use than the 7-day diary and pedometer.
480 citations
Authors
Showing all 10902 results
Name | H-index | Papers | Citations |
---|---|---|---|
John Q. Trojanowski | 226 | 1467 | 213948 |
Dorret I. Boomsma | 176 | 1507 | 136353 |
Brenda W.J.H. Penninx | 170 | 1139 | 119082 |
Michael John Owen | 160 | 1110 | 135795 |
Lex M. Bouter | 158 | 767 | 103034 |
Frederik Barkhof | 154 | 1449 | 104982 |
Ichiro Kawachi | 149 | 1216 | 90282 |
Walter Paulus | 149 | 809 | 86252 |
Philip Scheltens | 140 | 1175 | 107312 |
Herbert Y. Meltzer | 137 | 1148 | 81371 |
Pim Cuijpers | 136 | 982 | 69370 |
Jeffrey S. Flier | 131 | 314 | 78430 |
Peter Tugwell | 129 | 948 | 125480 |
Gonneke Willemsen | 129 | 575 | 76976 |
Chris J.L.M. Meijer | 128 | 733 | 78705 |