Institution
Zhejiang University
Education•Hangzhou, Zhejiang, China•
About: Zhejiang University is a education organization based out in Hangzhou, Zhejiang, China. It is known for research contribution in the topics: Catalysis & Population. The organization has 161257 authors who have published 183264 publications receiving 3417592 citations. The organization is also known as: Chekiang University & Zheda.
Topics: Catalysis, Population, Computer science, Medicine, Cancer
Papers published on a yearly basis
Papers
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TL;DR: Efforts are needed to establish a national system of dementia care enhance training in dementia for health professionals, and develop global collaborations to prevent and cure this disease.
Abstract: China has the largest population of patients with dementia in the world, imposing a heavy burden on the public and health care systems. More than 100 epidemiological studies on dementia have been done in China, but the estimates of the prevalence and incidence remain inconsistent because of the use of different sampling methods. Despite improved access to health services, inadequate diagnosis and management for dementia is still common, particularly in rural areas. The Chinese Government issued a new policy to increase care facilities for citizens older than 65 years, but most patients with dementia still receive care at home. Western medicines for dementia symptoms are widely used in China, but many patients choose Chinese medicines even though they have little evidence supporting efficacy. The number of clinical trials of Chinese and western medicines has substantially increased as a result of progress in research on new antidementia drugs but international multicentre studies are few in number. Efforts are needed to establish a national system of dementia care enhance training in dementia for health professionals, and develop global collaborations to prevent and cure this disease.
334 citations
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TL;DR: In this article, an adaptive sliding control method is presented for an electro-hydraulic system with nonlinear unknown parameters, which enter the system equations in a nonlinear way. But in practical hydraulic systems, the original control volumes are unknown or change; as a result some unknown parameters appear nonlinearly.
334 citations
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Capital Medical University1, Shandong University2, Wuhan University3, Jilin University4, Chongqing Medical University5, Sun Yat-sen University6, Zhejiang University7, Third Military Medical University8, Xi'an Jiaotong University9, Fudan University10, Qingdao University11, Central South University12, China-Japan Friendship Hospital13, Henry Ford Hospital14, McGill University15
TL;DR: The socioeconomic costs of Alzheimer's disease in China and its impact on global economic burden remain uncertain.
Abstract: Introduction The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. Methods We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD. Results The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015. Discussion China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide.
334 citations
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TL;DR: This is the first report on the top‐down fabrication of ultrathin 2D B NSs by the combined thermal oxidation etching and liquid exfoliation, as well as their application as a multimodal imaging‐guided drug delivery platform.
Abstract: Single atom nonmetal 2D nanomaterials have shown considerable potential in cancer nanomedicines, owing to their intriguing properties and biocompatibility. Herein, ultrathin boron nanosheets (B NSs) are prepared through a novel top-down approach by coupling thermal oxidation etching and liquid exfoliation technologies, with controlled nanoscale thickness. Based on the PEGylated B NSs, a new photonic drug delivery platform is developed, which exhibits multiple promising features for cancer therapy and imaging, including: i) efficient NIR-light-to-heat conversion with a high photothermal conversion efficiency of 42.5%, ii) high drug-loading capacity and triggered drug release by NIR light and moderate acidic pH, iii) strong accumulation at tumor sites, iv) multimodal imaging properties (photoacoustic, photothermal, and fluorescence imaging), and v) complete tumor ablation and excellent biocompatibility. As far as it is known, this is the first report on the top-down fabrication of ultrathin 2D B NSs by the combined thermal oxidation etching and liquid exfoliation, as well as their application as a multimodal imaging-guided drug delivery platform. The newly prepared B NSs are also expected to provide a robust and useful 2D nanoplatform for various biomedical applications.
334 citations
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TL;DR: In this article, a non-fullerene electron acceptor, called SF(DPPB)4, was designed and synthesized for poly(3-hexyl thiophene) (P3HT) donor in polymer solar cells (PSCs).
Abstract: In this study, we design and synthesize a new non-fullerene electron acceptor, SF(DPPB)4, in which a spirobifluorene (SF) core is installed with four benzene endcapped diketopyrrolopyrrole (DPP) arms. SF(DPPB)4 exhibits energy levels matching perfectly with those of the commonly used poly(3-hexyl thiophene) (P3HT) donor in polymer solar cells (PSCs). Furthermore, a designed cross-shaped molecular geometry helps in suppressing strong intermolecular aggregation in the P3HT : SF(DPPB)4 blend, leading to efficient non-fullerene PSCs. The resultant devices give a maximum power conversion efficiency (PCE) of 5.16% with an extremely high open-circuit voltage (Voc) of 1.14 V. In contrast, the devices based on P3HT : PC61BM blends provide a PCE of 3.18% with a Voc of 0.62 V. Finally, we observe that the P3HT : SF(DPPB)4 devices exhibit significantly improved thermal stability from that of the P3HT : PC61BM devices; upon thermal treatment at 150 °C for 3 h, the PCEs of P3HT : SF(DPPB)4 devices remain unchanged, whereas those of the P3HT : PC61BM devices drop drastically to below 1%. The abovementioned results demonstrate that the new design strategy of employing a high-performance non-fullerene acceptor, SF(DPPB)4, is promising for the future practical application of PSCs.
333 citations
Authors
Showing all 162389 results
Name | H-index | Papers | Citations |
---|---|---|---|
Stuart H. Orkin | 186 | 715 | 112182 |
H. S. Chen | 179 | 2401 | 178529 |
Markus Antonietti | 176 | 1068 | 127235 |
Yang Yang | 171 | 2644 | 153049 |
Gang Chen | 167 | 3372 | 149819 |
Jun Wang | 166 | 1093 | 141621 |
Hua Zhang | 163 | 1503 | 116769 |
Rui Zhang | 151 | 2625 | 107917 |
Ben Zhong Tang | 149 | 2007 | 116294 |
J. Fraser Stoddart | 147 | 1239 | 96083 |
Yi Yang | 143 | 2456 | 92268 |
Jian Yang | 142 | 1818 | 111166 |
Liming Dai | 141 | 781 | 82937 |
Joseph Lau | 140 | 1048 | 99305 |
Wei Huang | 139 | 2417 | 93522 |