Journal ArticleDOI
Advances in crosslinking strategies of biomedical hydrogels
Reads0
Chats0
TLDR
The commonly used crosslinking method for hydrogel synthesis involving physical and chemical crosslinks is presented and their current progress and future perspectives are summarized.Abstract:
Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and bioactive growth factors are extensively applied in tissue engineering and regenerative medicine. Hydrogels normally provide three dimensional structures for cell adhesion and proliferation or the controlled release of the loading of drugs or proteins. Various physiochemical properties of hydrogels endow them with distinct applications. In this review, we present the commonly used crosslinking method for hydrogel synthesis involving physical and chemical crosslinks and summarize their current progress and future perspectives.read more
Citations
More filters
Journal Article
Determining Beta Sheet Crystallinity in Fibrous Proteins by Thermal Analysis and Infrared Spectroscopy
TL;DR: In this article, B. mori silk fibroin films were studied thermally using temperature-modulated differential scanning calorimetry (TMDSC) to obtain the reversing heat capacity.
Journal ArticleDOI
Printability and Shape Fidelity of Bioinks in 3D Bioprinting.
Andrea Schwab,Riccardo Levato,Matteo D'Este,Susanna Piluso,Susanna Piluso,David Eglin,Jos Malda +6 more
TL;DR: The physicochemical parameters influencing shape fidelity are discussed, together with their importance in establishing new models, predictive tools and printing methods that are deemed instrumental for the design of next-generation bioinks, and for reproducible comparison of their structural performance.
Journal ArticleDOI
Scaffold fabrication technologies and structure/function properties in bone tissue engineering
TL;DR: A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided and strategies to improve vascularization potential and immunomodulation are presented.
Journal ArticleDOI
Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting
Farhad Abasalizadeh,Sevil Vaghefi Moghaddam,Effat Alizadeh,Elahe Akbari,Elmira Kashani,Seyyed Mohammad Bagher Fazljou,Mohammadali Torbati,Abolfazl Akbarzadeh,Abolfazl Akbarzadeh +8 more
TL;DR: The application of the alginate hydrogels will be defined as drug delivery vehicles for chemotherapeutic agents and the recent advances in the application will be described later as a wound dressing and bioink in 3D bioprinting.
Journal ArticleDOI
Commercial hydrogels for biomedical applications.
TL;DR: This paper focuses on the commercially available hydrogels used for biomedical applications like wound dressings, contact lenses, cosmetic applications, tissue engineering, and drug delivery.
References
More filters
Journal ArticleDOI
Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
TL;DR: In this paper, a set of powerful, highly reliable, and selective reactions for the rapid synthesis of useful new compounds and combinatorial libraries through heteroatom links (C-X-C), an approach called click chemistry is defined, enabled, and constrained by a handful of nearly perfect "springloaded" reactions.
Journal ArticleDOI
Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
TL;DR: This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
Journal ArticleDOI
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology†
TL;DR: This work highlights recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for biomedical and biological applications and shows how such systems' intelligent behavior can be used in sensors, microarrays, and imaging.
Journal ArticleDOI
Thiol–Ene Click Chemistry
TL;DR: The radical-mediated thiol-ene reaction has all the desirable features of a click reaction, being highly efficient, simple to execute with no side products and proceeding rapidly to high yield.