Aseptic loosening, not only a question of wear: a review of different theories.
TLDR
It emerges from this review that aseptic loosening has a multifactorial etiology and cannot be explained by a single theory.Abstract:
Today, aseptic loosening is the most common cause of revision of major arthroplasties. Aseptic loosening accounts for more than two-thirds of hip revisions and almost one-half of knee revisions in Sweden. Several theories on the cause of aseptic loosening have been proposed. Most of these theories, however, are based on empiric observations, experimental animal models or anecdotal cases. In this review, we discuss the most common theories concerning aseptic loosening. It emerges from this review that aseptic loosening has a multifactorial etiology and cannot be explained by a single theory.read more
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Periprosthetic Bone Loss in Total Hip Arthroplasty: Polyethylene Wear Debris and the Concept of the Effective Joint Space
TL;DR: The concept of the effective joint space is suggested to include all periprosthetic regions that are accessible to joint fluid and thus accessible to particulate debris to indicate that joint fluid penetrates far more extensively than previously thought.