Journal ArticleDOI
Critical limb ischemia.
David L. Dawson,Joseph L. Mills +1 more
TLDR
Surgical treatment is also indicated for failures of endovascular therapy, which may include early technical failures or later occlusion after placement of stents or other interventions.Abstract:
Critical limb ischemia (CLI) is the most severe manifestation of peripheral artery disease (PAD). Without timely recognition, appropriate diagnosis, and revascularization, patients with CLI are at risk for amputation or potentially fatal complications. The past decade has seen substantial growth in endovascular CLI therapies and options now exist for treating long-segment lower-extremity arterial occlusive disease, but surgical bypass may yield more durable results. Patients who are younger, more active, and at low risk for surgery may have better outcomes with an operation. Surgical treatment is also indicated for failures of endovascular therapy, which may include early technical failures or later occlusion after placement of stents or other interventions.read more
Citations
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Journal ArticleDOI
Global vascular guidelines on the management of chronic limb-threatening ischemia
Michael S. Conte,Andrew W. Bradbury,Philippe Kolh,John V. White,Florian Dick,Robert Fitridge,Joseph L. Mills,Jean-Baptiste Ricco,Kalkunte R Suresh,M. Hassan Murad,Victor Aboyans,Murat Aksoy,Vlad-Adrian Alexandrescu,David G. Armstrong,Nobuyoshi Azuma,Jill J. F. Belch,Michel Bergoeing,Martin Björck,Nabil Chakfe,Stephen W.K. Cheng,Joseph Dawson,Eike Sebastian Debus,Andrew Dueck,Sue Duval,Hans-Henning Eckstein,Roberto Ferraresi,Raghvinder Gambhir,Mauro Gargiulo,Patrick J. Geraghty,Steve Goode,Bruce H. Gray,Wei Guo,Prem C. Gupta,Robert J. Hinchliffe,Prasad Jetty,Kimihiro Komori,Lawrence A. Lavery,Wei Liang,Robert A. Lookstein,Matthew T. Menard,Sanjay Misra,Tetsuro Miyata,Greg Moneta,Jose A. Munoa Prado,Alberto Munoz,Juan E. Paolini,Manesh R. Patel,Frank B. Pomposelli,Richard J. Powell,Peter A Robless,Lee C. Rogers,Andres Schanzer,Peter Schneider,Spence M. Taylor,Melina Vega de Ceniga,Martin Veller,Frank Vermassen,Jinsong Wang,Shenming Wang +58 more
TL;DR: The GVG proposes a new Global Anatomic Staging System (GLASS), which involves defining a preferred target artery path (TAP) and then estimating limb-based patency (LBP) resulting in three stages of complexity for intervention.
Journal ArticleDOI
Adherence to Guideline‐Recommended Therapy Is Associated With Decreased Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients With Peripheral Arterial Disease
Ehrin J. Armstrong,Debbie C. Chen,Gregory G. Westin,Satinder Singh,Caroline E. McCoach,Heejung Bang,Khung-Keong Yeo,David E. Anderson,Ezra A. Amsterdam,John R. Laird +9 more
TL;DR: In patients with claudication or CLI, combination treatment with four guideline‐recommended therapies is associated with significant reductions in MACE, MALE, and mortality.
Journal ArticleDOI
Critical Limb Ischemia: Current Trends and Future Directions
TL;DR: Critical limb ischemia (CLI) is at the end of the peripheral artery disease (PAD) spectrum and is associated with excessively high risk for cardiovascular events, including myocardial infarction, and death.
Journal ArticleDOI
Chapter I: Definitions, Epidemiology, Clinical Presentation and Prognosis
François Becker,Helia Robert-Ebadi,J.-B. Ricco,Carlo Setacci,Piergiorgio Cao,G de Donato,Hans-Henning Eckstein,P. De Rango,Nicolas Diehm,Jürg Schmidli,Martin Teraa,F.L. Moll,Florian Dick,Alun H. Davies,Mauri Lepäntalo,Mauri Lepäntalo,Jan Apelqvist +16 more
TL;DR: Overall, CLI as defined by clinical and haemodynamic criteria remains a severe condition with poor prognosis, high medical costs and a major impact in terms of public health and patients' loss of functional capacity.
Journal ArticleDOI
Critical limb ischemia: definition and natural history.
TL;DR: Patients with critical limb ischemia have an elevated risk of future myocardial infarction, stroke and vascular death, 3-fold higher than patients with intermittent claudication, and due to its negative impact on the quality of life and the poor prognosis both in terms of limb salvage and survival, critical limb waschemia is a critical public health issue.
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