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Journal ArticleDOI

Enantioselective Toxicity and Carcinogenesis

Imran Ali, +2 more
- 01 Jan 2005 - 
- Vol. 1, Iss: 1, pp 109-125
TLDR
In a non-chiral environment, the enantiomers of a racemate possess the same physico-chemical properties but in the biological systems they possess different activities, so the knowledge of the stereoselective metabolisms of the chiral pollutants may be useful for the treatment of cancer and other diseases.
Abstract
In a non-chiral environment, the enantiomers of a racemate possess the same physico-chemical properties but in the biological systems they possess different activities. One of the enantiomers may be more toxic or carcinogenic, and, therefore, the present data available on the toxicity and carcinogenesis of the racemic mixtures of these chiral pollutants are not reliable and need modification in terms of the enantioselective toxicity and carcinogenesis. It is essential to explore the enantioselective toxicity and carcinogenesis due to the different enantiomers of the chiral pollutants. The knowledge of the stereoselective metabolisms of the chiral pollutants may be useful for the treatment of cancer and other diseases. The enantioselective toxicity and carcinogenesis due to the chiral pesticides, pollutants and some drugs have been discussed in this review article.

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Health and environmental effects of persistent organic pollutants

TL;DR: In this paper, the authors describe the recent studies on the health and environmental problems due to pollution of persistent organic pollutants (POPs) and future prospectives, convention and regulation, control and removal measures of POPs have also been discussed.
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New generation nano-adsorbents for the removal of emerging contaminants in water

TL;DR: In this paper, the state-of-the-art of the removal of new emerging pollutants using new generation nano-adsorbents by adsorption technology is described and the efforts are made to discuss the sources contamination and toxicities of new emergent pollutants, preparation, characterization and separation of new generation adaption technology.
Journal ArticleDOI

Chemical chiral pollution: Impact on the society and science and need of the regulations in the 21st century.

TL;DR: It is an urgent need of the present 21st century to develop a data bank on the chiral pollutants, guidelines for controlling the production, sale and use of the racemic agrochemicals and the other industrial products.
Journal ArticleDOI

Stereoselective uptake and degradation of (±)-o,p-DDD pesticide stereomers in water-sediment system.

TL;DR: The environmental stereoselective uptake and degradation of (±)-o,p-DDD pesticide stereomers in water-sediment system are described and are very useful to control the environmental contamination due to the chiral o, p- DDD pesticide as its two enantiomers have different ecological toxicities.
Journal ArticleDOI

Enantioselective degradation and ecotoxicity of the chiral herbicide diclofop in three freshwater alga cultures.

TL;DR: It was concluded that the enantioselective degradation and toxicity of chiral herbicides may result in their ecotoxicological effects being difficult to predict and that specific attention should thus be paid to currently used racemic pesticides as less active or inactive enantiomers may pose higher ecological risks.
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