Journal ArticleDOI
Global Solutions of Some Chemotaxis and Angiogenesis Systems in High Space Dimensions
TLDR
In this paper, two simple conservative systems of parabolic-elliptic and parabolicdegenerate type arising in modeling chemotaxis and angiogenesis were considered, and it was shown that weak solutions (which are equi-integrable in L1) exist even for large initial data.Abstract:
We consider two simple conservative systems of parabolic-elliptic and parabolic-degenerate type arising in modeling chemotaxis and angiogenesis. Both systems share the same property that when the
% MathType!Translator!2!1!AMS LaTeX.tdl!TeX -- AMS-LaTeX!
% MathType!MTEF!2!1!+-
% feaafiart1ev1aqatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn
% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr
% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqqrFfpeea0xe9Lq-Jc9
% vqaqpepm0xbba9pwe9Q8fs0-yqaqpepae9pg0FirpepeKkFr0xfr-x
% fr-xb9adbaqaaeGaciGaaiaabeqaamaabaabaaGcbaGaamitamaaCa
% aaleqabaWaaSaaaeaacaWGKbaabaGaaGOmaaaaaaaaaa!38A1!
$$L^{\frac{d}
{2}} $$
norm of initial data is small enough, where d ≥ 2 is the space dimension, then there is a global (in time) weak solution that stays in all the L
p
spaces with max
% MathType!Translator!2!1!AMS LaTeX.tdl!TeX -- AMS-LaTeX!
% MathType!MTEF!2!1!+-
% feaafiart1ev1aqatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn
% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr
% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqqrFfpeea0xe9Lq-Jc9
% vqaqpepm0xbba9pwe9Q8fs0-yqaqpepae9pg0FirpepeKkFr0xfr-x
% fr-xb9adbaqaaeGaciGaaiaabeqaamaabaabaaGcbaWaaiqaaeaada
% GacaqaaiaaigdacaGG7aWaaSaaaeaacaWGKbaabaGaaGOmaaaacqGH
% sislcaaIXaaacaGL9baacqGHKjYOcaWGWbGaeyipaWJaeyOhIuQaai
% OlaaGaay5Eaaaaaa!42CD!
$$\left\{ {\left. {1;\frac{d}
{2} - 1} \right\} \leq p < \infty .} \right.$$
This result is already known for the parabolic-elliptic system of chemotaxis, moreover blow-up can occur in finite time for large initial data and Dirac concentrations can occur. For the parabolic-degenerate system of angiogenesis in two dimensions, we also prove that weak solutions (which are equi-integrable in L1) exist even for large initial data. But break-down of regularity or propagation of smoothness is an open problem.read more
Citations
More filters
Journal ArticleDOI
A user’s guide to PDE models for chemotaxis
Thomas Hillen,Kevin J. Painter +1 more
TL;DR: This paper explores in detail a number of variations of the original Keller–Segel model of chemotaxis from a biological perspective, contrast their patterning properties, summarise key results on their analytical properties and classify their solution form.
Journal ArticleDOI
Aggregation vs. global diffusive behavior in the higher-dimensional Keller–Segel model
TL;DR: In this article, the authors considered the classical parabolic-parabolic Keller-Segel system with homogeneous Neumann boundary conditions in a smooth bounded domain and proved that for each q > n 2 and p > n one can find e 0 > 0 such that if the initial data ( u 0, v 0 ) satisfy L q ( Ω ) e and ∇ v 0 ‖ L p (Ω) e then the solution is global in time and bounded and asymptotically behaves like the solution of a discoupled system of linear parabolic
Journal ArticleDOI
Toward a mathematical theory of Keller–Segel models of pattern formation in biological tissues
TL;DR: In this article, a survey and critical analysis focused on a variety of chemotaxis models in biology, namely the classical Keller-Segel model and its subsequent modifications, which, in several cases, have been developed to obtain models that prevent the non-physical blow up of solutions.
Journal Article
Two-dimensional Keller-Segel model: Optimal critical mass and qualitative properties of the solutions
TL;DR: The Keller-Segel system describes the collective motion of cells which are attracted by a chemical substance and are able to emit it in its simplest form it is a conservative drift-diffusion equation coupled to an elliptic equation for the chemo-attractant concentration as mentioned in this paper.
Journal ArticleDOI
Global Solutions to the Coupled Chemotaxis-Fluid Equations
TL;DR: In this paper, a model arising from biology, which is a coupled system of the chemotaxis equations and the viscous incompressible fluid equations through transport and externa...
References
More filters
Book
Partial Differential Equations
TL;DR: In this paper, the authors present a theory for linear PDEs: Sobolev spaces Second-order elliptic equations Linear evolution equations, Hamilton-Jacobi equations and systems of conservation laws.
Journal ArticleDOI
Initiation of slime mold aggregation viewed as an instability.
Evelyn Fox Keller,Lee A. Segel +1 more
TL;DR: A mathematical formulation of the general interaction of amoebae, as mediated by acrasin is presented, and a detailed analysis of the aggregation process is provided.
Journal ArticleDOI
Model for Chemotaxis
Evelyn Fox Keller,Lee A. Segel +1 more
TL;DR: The chemotactic response of unicellular microscopic organisms is viewed as analogous to Brownian motion, and a macroscopic flux is derived which is proportional to the chemical gradient.
From 1970 until present: the Keller-Segel model in chemotaxis and its consequences
TL;DR: This article summarizes various aspects and results for some general formulations of the classical chemotaxis models also known as Keller-Segel models and offers possible generalizations of these results to more universal models.
Related Papers (5)
Initiation of slime mold aggregation viewed as an instability.
Evelyn Fox Keller,Lee A. Segel +1 more
On explosions of solutions to a system of partial differential equations modelling chemotaxis
Willi Jäger,Stephan Luckhaus +1 more