Journal ArticleDOI
Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS.
TLDR
Results from these studies reveal considerable support for longitudinal associations between cognition and community outcome in schizophrenia and demonstrate that cognitive assessment predict later functional outcome and provide a rationale for psychopharmacological interventions for cognitive deficits in schizophrenia.About:
This article is published in Schizophrenia Research.The article was published on 2004-12-15. It has received 1355 citations till now. The article focuses on the topics: Cognition & Schizophrenia (object-oriented programming).read more
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The MATRICS Consensus Cognitive Battery, Part 1: Test Selection, Reliability, and Validity
Keith H. Nuechterlein,Michael F. Green,Robert S. Kern,Lyle E. Baade,M Deanna,Jonathan D. Cohen,Susan M. Essock,Wayne S. Fenton,Frederick J. Frese,James M. Gold,Terry E. Goldberg,Robert K. Heaton,Richard S.E. Keefe,Helena C. Kraemer,Raquelle I. Mesholam-Gately,Larry J. Seidman,Ellen Stover,Daniel R. Weinberger,Alexander S. Young,Steven Zalcman,Stephen R. Marder +20 more
TL;DR: The MATRICS Consensus Cognitive Battery is expected to be the standard tool for assessing cognitive change in clinical trials of cognition-enhancing drugs for schizophrenia and may also aid evaluation of cognitive remediation strategies.
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The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis.
Anne-Kathrin Fett,Wolfgang Viechtbauer,Maria de Gracia Dominguez,David L. Penn,Jim van Os,Lydia Krabbendam +5 more
TL;DR: Overall, social cognition was more strongly associated with community functioning than neurocognition, with the strongest associations being between theory of mind and functional outcomes.
Journal ArticleDOI
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
Millan Mark,Yves Agid,Martin Brüne,Edward T. Bullmore,Cameron S. Carter,Nicola S. Clayton,Richard C. Connor,Sabrina Davis,Bill Deakin,Robert J. DeRubeis,Bruno Dubois,Mark A. Geyer,Guy M. Goodwin,Philip Gorwood,Thérèse M. Jay,Marian Joëls,Isabelle M. Mansuy,Andreas Meyer-Lindenberg,Declan G. Murphy,Edmund T. Rolls,Bernd Saletu,Michael Spedding,John A. Sweeney,Miles A. Whittington,Larry J. Young +24 more
TL;DR: This article critically discusses the challenges and opportunities for improving cognition in individuals suffering from psychiatric disorders, highlighting the needs to characterize the cellular and cerebral circuits underpinning cognitive function and identify more effective treatments.
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Cognitive impairment and functional outcome in schizophrenia and bipolar disorder.
TL;DR: Evidence is beginning to emerge that cognitive impairment may also be a core feature of bipolar disorder and this evidence suggests that cognition can be considered a reasonable target for intervention in both schizophrenia and bipolar disorder.
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Preliminary Findings for Two New Measures of Social and Role Functioning in the Prodromal Phase of Schizophrenia
Barbara A. Cornblatt,Andrea M. Auther,Tara A. Niendam,Christopher W. Smith,Jamie Zinberg,Carrie E. Bearden,Tyrone D. Cannon +6 more
TL;DR: Using 2 new global measures, social functioning was found to be a stable trait, unchanged by treatment, with considerable potential to been a marker of schizophrenia.
References
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Book
Statistical Power Analysis for the Behavioral Sciences
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
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What are the functional consequences of neurocognitive deficits in schizophrenia
TL;DR: Verbal memory and vigilance appear to be necessary for adequate functional outcome in schizophrenic patients and may prevent patients from attaining optimal adaptation and hence act as "neurocognitive rate-limiting factors."
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Neurocognitive Deficits and Functional Outcome in Schizophrenia: Are We Measuring the “Right Stuff”?
TL;DR: This paper will attempt to confirm the conclusions from a previous review that certain neurocognitive domains (secondary verbal memory, immediate memory, executive functioning as measured by card sorting, and vigilance) are associated with functional outcome.
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The Quality of Life Scale: An Instrument for Rating the Schizophrenic Deficit Syndrome
TL;DR: The authors describe the Quality of Life Scale (QLS), a 21-item scale based on a semistructured interview designed to assess deficit symptoms and thereby fill an important gap in the range of instruments now available.
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A Quality of Life Interview for the chronically mentally ill.
TL;DR: The development and psychometric evaluation of a structured, 45-minute Quality of Life Interview for the chronically mentally ill is described, which has satisfactory reliability and validity.