Journal ArticleDOI
Near-infrared fluorophores for biomedical imaging
TLDR
This Review covers recent progress on near-infrared fluorescence imaging for preclinical animal studies and clinical diagnostics and interventions.Abstract:
This Review covers recent progress on near-infrared fluorescence imaging for preclinical animal studies and clinical diagnostics and interventions.read more
Citations
More filters
Journal ArticleDOI
Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation
Jingchao Li,Kanyi Pu +1 more
TL;DR: This review summarizes the recent progress in the development of OSMs based on small-molecule fluorophores, aggregation-induced emission (AIE) dyes and semiconducting oligomer/polymer nanoparticles (SONs/SPNs) for advanced biophotonic applications and highlights OSMs as a multifunctional platform for a wide range of biomedical applications.
Journal ArticleDOI
Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics
TL;DR: Recent advances in the chemical design and synthesis of NIR-II fluorophores from small organic molecules to organic and inorganic nanoparticles and the presence of simultaneous diagnostic and therapeutic capabilities in a single probe are focused on.
Journal ArticleDOI
Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery.
TL;DR: This review focuses on summarizing organic dyes emitting at a biological transparency window termed the near‐infrared‐II (NIR‐II) window, where minimal light interaction with the surrounding tissues allows photons to travel nearly unperturbed throughout the body.
Journal ArticleDOI
First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows
Zhenhua Hu,Cheng Fang,Bo Li,Zeyu Zhang,Zeyu Zhang,Caiguang Cao,Meishan Cai,Song Su,Xingwang Sun,Xiaojing Shi,Cong Li,Tie-Jun Zhou,Yuanxue Zhang,Chongwei Chi,Pan He,Xianming Xia,Yue Chen,Sanjiv S. Gambhir,Zhen Cheng,Jie Tian +19 more
TL;DR: It is inferred that combining the NIR-I/II spectral windows and suitable fluorescence probes might improve image-guided surgery in the clinic and help the fluorescence-guided surgical resection of liver tumours in patients.
Journal ArticleDOI
Recent Advances of Optical Imaging in the Second Near-Infrared Window
Kenry,Yukun Duan,Bin Liu +2 more
TL;DR: The importance of biological imaging in the NIR‐II spectral region is highlighted, the emergence and latest development of various Nir‐II fluorescence and PA imaging probes and their applications are discussed, and Perspectives on the promises and challenges facing this nascent yet exciting field are given.
References
More filters
Book
Principles of fluorescence spectroscopy
TL;DR: This book describes the fundamental aspects of fluorescence, the biochemical applications of this methodology, and the instrumentation used in fluorescence spectroscopy.
Journal ArticleDOI
Aggregation-Induced Emission: Together We Shine, United We Soar!
TL;DR: This paper presents a meta-analysis of the chiral stationary phase transition of Na6(CO3)(SO4)2, a major component of the response of the immune system to Na2CO3.
Journal ArticleDOI
Principles of nanoparticle design for overcoming biological barriers to drug delivery
TL;DR: By successively addressing each of the biological barriers that a particle encounters upon intravenous administration, innovative design features can be rationally incorporated that will create a new generation of nanotherapeutics, realizing a paradigmatic shift in nanoparticle-based drug delivery.
Journal ArticleDOI
Renal clearance of quantum dots.
Hak Soo Choi,Wenhao Liu,Preeti Misra,Eiichi Tanaka,John P. Zimmer,Binil Itty Ipe,Moungi G. Bawendi,John V. Frangioni,John V. Frangioni +8 more
TL;DR: This study has precisely defined the requirements for renal filtration and urinary excretion of inorganic, metal-containing nanoparticles and provides a foundation for the design and development of biologically targeted nanoparticles for biomedical applications.
Journal ArticleDOI
Band gap fluorescence from individual single-walled carbon nanotubes.
Michael J. O'Connell,Sergei M. Bachilo,Chad B. Huffman,Valerie C. Moore,Michael S. Strano,Erik H. Haroz,Kristy L. Rialon,Peter J. Boul,William H. Noon,Carter Kittrell,Jianpeng Ma,Jianpeng Ma,Robert H. Hauge,R. Bruce Weisman,Richard E. Smalley +14 more
TL;DR: At pH less than 5, the absorption and emission spectra of individual nanotubes show evidence of band gap–selective protonation of the side walls of the tube, which is readily reversed by treatment with base or ultraviolet light.