Journal ArticleDOI
Recent Advances of Optical Imaging in the Second Near-Infrared Window
Kenry,Yukun Duan,Bin Liu +2 more
TLDR
The importance of biological imaging in the NIR‐II spectral region is highlighted, the emergence and latest development of various Nir‐II fluorescence and PA imaging probes and their applications are discussed, and Perspectives on the promises and challenges facing this nascent yet exciting field are given.Abstract:
The near-infrared window between 1000 and 1700 nm, commonly termed the "second near-infrared (NIR-II) window," has quickly emerged as a highly attractive optical region for biological imaging. In contrast to conventional imaging in the visible region between 400 and 700 nm, as well as in the first NIR (NIR-I) window between 700 and 900 nm, NIR-II biological imaging offers numerous merits, including higher spatial resolution, deeper penetration depth, and lower optical absorption and scattering from biological substrates with minimal tissue autofluorescence. Noninvasive imaging techniques, specifically NIR-II fluorescence and photoacoustic (PA) imaging, have embodied the attractiveness of NIR-II optical imaging, with several NIR-II contrast agents demonstrating superior performance to the clinically approved NIR-I agents. Consequently, NIR-II biological imaging has been increasingly explored due to its tremendous potential for preclinical studies and clinical utility. Herein, the progress of optical imaging in the NIR-II window is reported. Starting with highlighting the importance of biological imaging in the NIR-II spectral region, the emergence and latest development of various NIR-II fluorescence and PA imaging probes and their applications are then discussed. Perspectives on the promises and challenges facing this nascent yet exciting field are then given.read more
Citations
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Journal ArticleDOI
Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery.
TL;DR: This review focuses on summarizing organic dyes emitting at a biological transparency window termed the near‐infrared‐II (NIR‐II) window, where minimal light interaction with the surrounding tissues allows photons to travel nearly unperturbed throughout the body.
Journal ArticleDOI
Supramolecular materials based on AIE luminogens (AIEgens): construction and applications
TL;DR: The emergence of aggregation-induced emission luminogens (AIEgens) has significantly stimulated the development of luminescent supramolecular materials because their strong emissions in the aggregated state have resolved the notorious obstacle of the aggregation-caused quenching (ACQ) effect.
Next-generation in vivo optical imaging with short-wave infrared quantum dots
Lars Riedemann,Alexander Bartelt,Frank B. Jaworski,Jonas Kloepper,Joerg Heeren,Peter T. C. So,Dai Fukumura,Rakesh K. Jain,Oliver T. Bruns,Thomas S. Bischof,Daniel K. Harris,Daniel Franke,Yanxiang Shi,Jessica A. Carr,Christopher J. Rowlands,Mark W. Wilson,Ou Chen,He Wei,Gyu Weon Hwang,Daniel M Montana Fernandez,Igor Coropceanu,Odin B. Achorn,Klavs F. Jensen,Moungi G. Bawendi +23 more
TL;DR: In this paper, a class of high-quality SWIR-emissive indium-arsenide-based quantum dots (QDs) are introduced for various functional imaging applications, and that exhibit narrow and size-tunable emission and a dramatically higher emission quantum yield than previously described SWIR probes.
Journal ArticleDOI
J-Aggregates of Cyanine Dye for NIR-II in Vivo Dynamic Vascular Imaging beyond 1500 nm
Caixia Sun,Benhao Li,Mengyao Zhao,Shangfeng Wang,Zuhai Lei,Lingfei Lu,Hongxin Zhang,Lishuai Feng,Chaoran Dou,Dongrui Yin,Huixiong Xu,Yingsheng Cheng,Fan Zhang +12 more
TL;DR: The efficacy evaluation of the clinically used hypotensor is successfully achieved by high-resolution in-vivo dynamic vascular imaging with J-aggregates for non-invasive brain and hindlimb vascula-ture bio-imaging beyond 1500 nm.
Journal ArticleDOI
GSH‐Depleted PtCu3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy
Xiaoyan Zhong,Xianwen Wang,Liang Cheng,Yong'an Tang,Guiting Zhan,Fei Gong,Rui Zhang,Jun Hu,Zhuang Liu,Xiangliang Yang +9 more
TL;DR: PtCu3 nanocages are first reported as acting as a sonosensitizer with highly efficient ROS generation under ultrasound irradiation, and can act as horseradish peroxidase‐like nanozymes, catalyzing the decomposition of H2O2 into •OH under acidic conditions for CDT.
References
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Journal ArticleDOI
Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs
Lihong V. Wang,Song Hu +1 more
TL;DR: A review of the state of the art of photoacoustic tomography for both biological and clinical studies can be found in this paper, where the authors discuss the current state-of-the-art and discuss future prospects.
Journal ArticleDOI
Photoacoustic imaging in biomedicine
Minghua Xu,Lihong V. Wang +1 more
TL;DR: An overview of the rapidly expanding field of photoacoustic imaging for biomedical applications can be found in this article, where a number of imaging techniques, including depth profiling in layered media, scanning tomography with focused ultrasonic transducers, image forming with an acoustic lens, and computed tomography using unfocused transducers are introduced.