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Open AccessJournal ArticleDOI

Probiotics in man and animals

R. Fuller
- 01 May 1989 - 
- Vol. 66, Iss: 5, pp 365-378
TLDR
In this paper, the authors used probiotic treatments to re-establish the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy.
Abstract
There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease. However, the composition of this protective flora can be altered by dietary and environmental influences, making the host animal susceptible to disease and/or reducing its efficiency of food utilization. What we are doing with the probiotic treatments is re-establishing the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy. These are all areas where the gut flora can be altered for the worse and where, by the administration of probiotics, the natural balance of the gut microflora can be restored and the animal returned to its normal nutrition, growth and health status.

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Citations
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Journal ArticleDOI

Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial

TL;DR: Gut microflora might be a hitherto unexplored source of natural immunomodulators and probiotics, for prevention of atopic disease in children at high risk.
Journal ArticleDOI

Dietary modulation of the human colonic microbiota: updating the concept of prebiotics

TL;DR: The future use of prebiotics may allow species-level changes in the microbiota, an extrapolation into genera other than the bifidobacteria and lactobacilli, and allow preferential use in disease-prone areas of the body.
Journal ArticleDOI

Probiotic Bacteria as Biological Control Agents in Aquaculture

TL;DR: This review describes the state of the art of probiotic research in the culture of fish, crustaceans, mollusks, and live food, with an evaluation of the results obtained so far.
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The interaction between bacteria and bile

TL;DR: The antimicrobial actions of bile are described, the variations in bile tolerance between bacterial genera are assessed and the relationship between bile and virulence is examined.
Journal ArticleDOI

Probiotics, prebiotics, and synbiotics—approaching a definition

TL;DR: The probiotic concept is confined to effects exerted by viable microorganisms but is applicable independent of the site of action and route of administration, and may include sites such as the oral cavity, the intestine, the vagina, and the skin.
References
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Journal ArticleDOI

Human fecal flora: the normal flora of 20 Japanese-Hawaiians.

TL;DR: Quantitative and qualitative examination of the fecal flora of 20 clinically healthy Japanese-Hawaiian males was carried out by using anaerobic tube culture techniques, and differential characteristics of previously unreported species are presented.
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Probiotics: Growth-Promoting Factors Produced by Microorganisms

TL;DR: A consistent 50-percent increase in growth has been obtained with Tetrahymena pyriformis in response to a factor produced by Colpidium campylum.
Journal ArticleDOI

New aspects of Salmonella infection in broiler production.

E. Nurmi, +1 more
- 19 Jan 1973 - 
TL;DR: POULTRY are a considerable reservoir of salmonellae and a common source of infection in human Salmonella epidemics, and in 1971 a severe outbreak ofSalmonella infantis infection occurred among Finnish broiler flocks.
Journal ArticleDOI

Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.

TL;DR: Germ-free mice contaminated with the intestinal flora of an antibiotic-treated animal and their offspring housed in a germ-free isolator showed high values of CR, and apparently, these anaerobes are responsible for CR in these and in conventional mice.
Journal ArticleDOI

Survival of Lactic Acid Bacteria in the Human Stomach and Adhesion to Intestinal Cells

TL;DR: An in vitro test system for screening potential cultures for use as human dietary adjuncts can be developed and from the survival and adhesion data it seems feasible to obtain elevated levels of viable Lactobacillus sp.
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