Journal ArticleDOI
Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria.
TLDR
Diagnostic criteria and some historical perspectives on the diagnosis of pyoderma gangrenosum are suggested.Abstract:
Pyoderma gangrenosum is a rare but significant cause of ulcerations. It is a diagnosis of exclusion. Herein, we suggest diagnostic criteria and some historical perspectives on the diagnosis of pyoderma gangrenosum.read more
Citations
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Journal ArticleDOI
Treating the chronic wound: A practical approach to the care of nonhealing wounds and wound care dressings
Margaret A. Fonder,Gerald S. Lazarus,David A. Cowan,Barbara Aronson-Cook,Angela R. Kohli,Adam J. Mamelak +5 more
TL;DR: This work emphasizes major aspects of diagnosis and presents a simple classification of wound dressings with guidelines for usage and relative cost data.
Journal ArticleDOI
Pyoderma gangrenosum: an updated review
TL;DR: Pyoderma gangrenosum often occurs in association with a systemic disease such as inflammatory bowel disease, rheumatologic disease, paraproteinaemia, or haematological malignancy, and long‐term treatment with these agents is often required, but this can expose patients to adverse side‐effects.
Journal ArticleDOI
Etiology and management of pyoderma gangrenosum: a comprehensive review.
TL;DR: Successful management of PG typically requires multiple modalities to reduce inflammation and optimize wound healing, in addition to treatment of any underlying diseases, such as tumor necrosis factor-a inhibitors for refractory cases of PG.
Journal ArticleDOI
Diagnostic criteria of ulcerative Pyoderma Gangrenosum a delphi consensus of international experts
Emanual Michael Maverakis,Chelsea Ma,Kanade Shinkai,David Fiorentino,Jeffrey P. Callen,Uwe Wollina,Angelo V. Marzano,Daniel Wallach,Kyoungmi Kim,Courtney R. Schadt,Anthony Ormerod,Maxwell A Fung,Andrea Steel,Forum Patel,Rosie Qin,Fiona Craig,Hywel C Williams,Frank C. Powell,Alexander A. Merleev,Michelle Y. Cheng +19 more
TL;DR: Diagnostic criteria were created following a Delphi consensus exercise and validated against peer-reviewed established cases of pyoderma gangrenosum and mimickers using k-fold cross-validation with methods of multiple imputation to serve as a guideline for clinicians.
Journal ArticleDOI
Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment.
TL;DR: This review is the management and evidence supporting the role of new targeted therapies in PG, a rare inflammatory neutrophilic disorder with prototypical clinical presentations.
References
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Journal ArticleDOI
The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients.
TL;DR: The records of a series of 700 patients with inflammatory bowel disease, 498 with Crohn's disease and 202 with ulcerative colitis, have been analyzed to determine the relative incidence and characteristic features of their extra-intestinal manifestations.
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Pyoderma gangrenosum: Classification and management
TL;DR: Pyoderma gangrenosum has four distinctive clinical and histologic variants and some have morphologic and Histologic overlapping features with other reactive neutrophilic skin conditions.
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Pyoderma gangrenosum: a review of 86 patients.
TL;DR: The clinical, histologic, and immunofluorescent findings in 86 cases of pyoderma gangrenosum seen at the Mayo Clinic between 1970 and 1983 were reviewed, finding lymphocytic vasculitis was predominant in the zone of erythema peripheral to the area of ulceration, while neutrophilic infiltrate and abscess formation were more prominent centrally.
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Pyoderma (echthyma) gangrenosum: clinical and experimental observations in five cases occurring in adults
TL;DR: During the period of observation in each case throughout a series of exacerbations and remissions, it appeared evident that there was a definite parallel relationship between the underlying debilitating disease and the cutaneous manifestations.
Journal ArticleDOI
Skin ulcers misdiagnosed as pyoderma gangrenosum.
TL;DR: A thorough evaluation is required in all patients suspected of having pyoderma gangrenosum in order to rule out alternative diagnoses, and it was clear that those in 23 patients did not respond to treatment directed at pyoderm gangrenoum, those in 8 were exacerbated by such treatment, and those in 15 improved with such treatment.