Open AccessJournal Article
The relationship between lipid profile and severity of liver damage in cirrhotic patients.
Mohammad Reza Ghadir,Ali Akbar Riahin,Abbas Havaspour,Mehrdad Nooranipour,Abbas Ali Habibinejad +4 more
TLDR
Comparison of lipid profile with pathologic progression of cirrhosis revealed that except for serum triglyceride level, serum lipid levels diminishe linearly with progression of liver damage.Abstract:
Background and Aims: An impaired lipid metabolism is often observed in patients with chronic liver diseases To determine lipid profile in patients with cirrhosis and to asses if it relates to the severity of the cirrhosis Materials and Methods: In an analytical cross-sectional study, 50 patients with cirrhosis (case) and 50 age- and sexmatched healthy normolipidemic patients (comparison) were studied A questionnaire including personal characteristics, etiology of cirrhosis, pathologic criteria of CHILD and MELD and lipid profile (total, LDL, and HDL cholesterol and triglyceride) was completed for each patient Results: In patients with cirrhosis, there was a significant decrease in serum triglyceride, total, LDL and HDL cholesterol levels compared to the comparison group (mean of 82 vs 187, 138 vs 184, 80 vs 137, and 40 vs 44 mg/dL, respectively; all p<005) Comparison of lipid profile with pathologic progression of cirrhosis revealed that except for serum triglyceride level, serum lipid levels diminishe linearly with progression of liver damage Conclusions: Serum total, LDL and HDL cholesterol level in patients with cirrhosis is inversely correlate with severity of cirrhosisread more
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Risk factors for metabolic syndrome after liver transplantation: A systematic review and meta-analysis.
TL;DR: The prevalences of metabolic syndrome and new-onset metabolic syndrome were high after liver transplantation and patients with pre-transplant diabetes and -obesity should be under careful surveillance to limit the risk of cardiovascular events.
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The association between individual metabolic syndrome components, primary liver cancer and cirrhosis: A study in the Swedish AMORIS cohort
Paul Nderitu,Cecilia Bosco,Hans Garmo,Hans Garmo,Lars Holmberg,Lars Holmberg,Håkan Malmström,Niklas Hammar,Göran Walldius,Ingmar Jungner,Paul Ross,Mieke Van Hemelrijck,Mieke Van Hemelrijck +12 more
TL;DR: This work investigated the association between the individual components of MetS (lipids, apolipoproteins, raised glucose, diabetes and obesity), PLC and cirrhosis.
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The Impact of Opium Consumption on Blood Glucose, Serum Lipids and Blood Pressure, and Related Mechanisms.
Hamid Najafipour,Ahmad Beik +1 more
TL;DR: Although opium may temporarily reduce blood pressure, but it increases blood glucose and most of blood lipids, its long term use has negative impacts and thus it aggravates diabetes, dyslipidemia and hypertension.
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Serum lipid profile as a marker of liver impairment in hepatitis B Cirrhosis patients
Sadia Qamar Arain,Farah Naz Talpur,Naseem Aslam Channa,Muhammad Shahbaz Ali,Hassan Imran Afridi +4 more
TL;DR: Hypolipidemia observed in HBV-cirrhosis patients, MELD were found to be independent predictors of survival and alteration in fatty acid composition, possibly due to impairment in fatty acids metabolism by enzymatic elongation and desaturation.
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A metabolic profiling analysis of the acute hepatotoxicity and nephrotoxicity of Zhusha Anshen Wan compared with cinnabar in rats using 1H NMR spectroscopy
TL;DR: The results suggested that the four combined herbal medicines of ZSASW had the effects of protecting from the toxicity induced by cinnabar alone, and showed that the NMR-based metabonomics approach might be a promising approach to study detoxification of Chinese medicines and reasonable combination of TCM prescriptions.
References
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Harrison's Principles of Internal Medicine
TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
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Serum Lipid and Lipoprotein Patterns in Patients With Liver Cirrhosis and Chronic Active Hepatitis
Camilla Cicognani,Mauro Malavolti,Antonio Maria Morselli-Labate,L Zamboni,Claudia Sama,Luigi Barbara +5 more
TL;DR: The striking decrease in the level of serum LDL cholesterol in patients with liver disease was related to the increasing severity of the disease and the assessment of the serum cholesterol level is important for an effective treatment and prognostic evaluation of patients with chronic liver disease.
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Serum lipid pattern in chronic hepatitis C: histological and virological correlations.
D. Siagris,Myrto Christofidou,George J Theocharis,Niki A. Pagoni,C Papadimitriou,Alexandra Lekkou,Konstantinos Thomopoulos,Ioannis Starakis,Athanassios C. Tsamandas,Chryssoula Labropoulou-Karatza +9 more
TL;DR: HCV infection is associated with clinically significant lower cholesterol levels (TC, LDL and HDL) when compared with those of normal subjects, and this finding is more pronounced in patients infected with HCV genotype 3a.
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Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review.
TL;DR: It is suggested that 12% of PBC patients died from circulatory system diseases suggesting that lipid treatment is appropriate in some patients, and additional larger scale, prospective studies are required to determine the necessity of lipid treatment in this patient group.
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Nutrition and alcoholic liver disease.
TL;DR: Several studies have evaluated the potential efficacies of oral, enteral, and parenteral nutrition approaches to treatment of ALD, with mixed results on liver function, clinical improvements, and short- or long-term survival.