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Open AccessJournal ArticleDOI

Toxoplasma gondii: transmission, diagnosis and prevention

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TLDR
Toxoplasmosis is one of the most common parasitic infections of man and other warm-blooded animals and can cause blindness and mental retardation in congenitally infected children and devastating disease in immunocompromised individuals.
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This article is published in Clinical Microbiology and Infection.The article was published on 2002-10-01 and is currently open access. It has received 1005 citations till now. The article focuses on the topics: Toxoplasma gondii & Toxoplasmosis.

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Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis

TL;DR: The authors sought to evaluate the current global status of T. gondii seroprevalence and its correlations with risk factors, environmental and socioeconomic parameters, and recognise specific risk factors related to seropositivity; however, such risk factors are not reported systematically.
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Fatal Outbreak of Human Toxoplasmosis along the Maroni River: Epidemiological, Clinical, and Parasitological Aspects

TL;DR: Molecular analysis demonstrated that identical isolates of only 1 atypical strain were responsible for at least 5 of the 11 cases of toxoplasmosis in the outbreak in Patam, a Surinamese village near the French Guianan border.
Journal ArticleDOI

Integrative Genomic Approaches Highlight a Family of Parasite-Specific Kinases that Regulate Host Responses

TL;DR: Transgenic parasite ROP38 downregulates host genes associated with MAPK signaling and the control of apoptosis and proliferation, highlighting the value of integrative genomic approaches in prioritizing candidates for functional validation.
References
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Journal ArticleDOI

Toxoplasma gondii: from animals to humans

TL;DR: Recent epidemiological data on T. gondii, hypotheses on the major routes of transmission to humans in different populations, and preventive measures that may reduce the risk of contracting a primary infection during pregnancy are presented.
Book

Infectious Diseases of the Fetus and Newborn Infant

TL;DR: Infectious diseases of the fetus and newborn infant, Infectious diseases in the fetus as mentioned in this paper, infection of the newborn infant and the mother, infection of a fetus and infection of an infant.
Journal ArticleDOI

Toxoplasmic Encephalitis in AIDS

TL;DR: This commentary comprises an update of their initial review of T. gondii and a presentation of the current approaches to diagnosing and managing toxoplasmic encephalitis in HIV-infected patients.
Journal ArticleDOI

Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction.

TL;DR: A combination of sensitivity and specificity should make detection of the B1 gene based on polymerase chain reaction amplification a very useful method for diagnosis of toxoplasmosis both in immunocompromised hosts and in congenitally infected fetuses.
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