Journal ArticleDOI
Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis
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TLDR
The authors sought to evaluate the current global status of T. gondii seroprevalence and its correlations with risk factors, environmental and socioeconomic parameters, and recognise specific risk factors related to seropositivity; however, such risk factors are not reported systematically.About:
This article is published in International Journal for Parasitology.The article was published on 2009-10-01. It has received 909 citations till now. The article focuses on the topics: Seroprevalence & Population.read more
Citations
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Journal ArticleDOI
Epidemiology of and Diagnostic Strategies for Toxoplasmosis
TL;DR: This review focuses on epidemiological and diagnostic aspects, putting them in perspective with current knowledge of parasite genotypes, and provides critical information on diagnostic methods according to the patient's background.
Journal ArticleDOI
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.
Saima M. Sidik,Diego Huet,Suresh M. Ganesan,My Hang Huynh,Timothy C. Wang,Timothy C. Wang,Armiyaw S. Nasamu,Prathapan Thiru,Jeroen P. J. Saeij,Vern B. Carruthers,Jacquin C. Niles,Sebastian Lourido +11 more
TL;DR: In this article, the authors adapted CRISPR/Cas9 to assess the contribution of each gene from the parasite Toxoplasma gondii during infection of human fibroblasts.
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The global burden of congenital toxoplasmosis: a systematic review
TL;DR: Congenital toxoplasmosis poses a substantial burden of poor health globally and should be included in future updates of the global burden of disease and the corresponding data should be used to support public health interventions to reduce disease burden.
Journal ArticleDOI
Toxoplasmosis – A Global Threat. Correlation of Latent Toxoplasmosis with Specific Disease Burden in a Set of 88 Countries
TL;DR: The precautionary principle suggests that possible role of toxoplasmosis as a triggering factor responsible for development of several clinical entities deserves much more attention and financial support both in everyday medical practice and future clinical research.
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
Saima M. Sidik,Diego Huet,My Hang Huynh,Prathapan Thiru,Jeroen P. J. Saeij,Vern B. Carruthers,Sebastian Lourido,Suresh M. Ganesan,Armiyaw S. Nasamu,Jacquin C. Niles,Timothy C. Wang +10 more
TL;DR: The first genome-wide genetic screen of an apicomplexan parasite is presented, revealing essential functions during infection of human cells and providing broad-based functional information on T. gondii genes that will facilitate future approaches to expand the horizon of antiparasitic interventions.
References
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Journal ArticleDOI
Food-related illness and death in the United States.
Paul S. Mead,Laurence Slutsker,Vance Dietz,Linda F. McCaig,Joseph S. Bresee,Craig N. Shapiro,Patricia M. Griffin,Robert V. Tauxe +7 more
TL;DR: Overall, foodborne diseases appear to cause more illnesses but fewer deaths than previously estimated.
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Toxoplasma gondii: from animals to humans
TL;DR: Recent epidemiological data on T. gondii, hypotheses on the major routes of transmission to humans in different populations, and preventive measures that may reduce the risk of contracting a primary infection during pregnancy are presented.
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Toxoplasma gondii: transmission, diagnosis and prevention
TL;DR: Toxoplasmosis is one of the most common parasitic infections of man and other warm-blooded animals and can cause blindness and mental retardation in congenitally infected children and devastating disease in immunocompromised individuals.
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Sources of toxoplasma infection in pregnant women: European multicentre case-control study
Alasdair J. C. Cook,Ruth Gilbert,Wilma Buffolano,J Zufferey,Eskild Petersen,P A Jenum,Walter Foulon,Augusto E. Semprini,David Dunn +8 more
TL;DR: Inadequately cooked or cured meat is the main risk factor for infection with toxoplasma in all centres and preventive strategies should aim to reduce prevalence of infection in meat, improve labelling of meat according to farming and processing methods, and improve the quality and consistency of health information given to pregnant women.
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Toxoplasmosis of the Central Nervous System in the Acquired Immunodeficiency Syndrome
Steven B. Porter,Merle A. Sande +1 more
TL;DR: Toxoplasmosis occurs in advanced stages of human immunodeficiency virus infection, and the absence of antitoxoplasma antibodies on immunofluorescence assay does not exclude the diagnosis.