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A. Richard Chamberlin
Researcher at University of California, Irvine
Publications - 112
Citations - 5857
A. Richard Chamberlin is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Total synthesis & Amino acid. The author has an hindex of 38, co-authored 111 publications receiving 5562 citations. Previous affiliations of A. Richard Chamberlin include University of California, San Diego & Exelixis.
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Chemical Synthesis of Natural Product Peptides: Coupling Methods for the Incorporation of Noncoded Amino Acids into Peptides.
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Biosynthetic site-specific incorporation of a non-natural amino acid into a polypeptide
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Increasing rates of reaction: microwave-assisted organic synthesis for combinatorial chemistry.
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Congener-independent immunoassay for microcystins and nodularins
Werner Fischer,Ian Garthwaite,Christopher O. Miles,Kathryn Marie Ross,James B. Aggen,A. Richard Chamberlin,Neale R. Towers,Daniel R. Dietrich +7 more
TL;DR: This new ELISA is robust, can be performed without sample preconcentration, detects toxins in freshwater samples at lower concentrations than does the protein phosphatase inhibition assay, and shows very good cross-reactivity with all cyanobacterial cyclic peptide toxin congeners tested to date.
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Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53
Christopher D. Wassman,Roberta Baronio,Özlem Demir,Özlem Demir,Brad D. Wallentine,Chiung-Kuang Chen,Linda V. Hall,Faezeh Salehi,Dawei Lin,Benjamin P. Chung,G. Wesley Hatfield,A. Richard Chamberlin,Hartmut Luecke,Richard H. Lathrop,Peter K. Kaiser,Rommie E. Amaro +15 more
TL;DR: In this paper, a transiently open binding pocket between loop L1 and sheet S3 of the p53 core domain was identified as a target for pharmaceutical reactivation of p53 mutants.