P
Peter O. Krutzik
Researcher at University of California, Irvine
Publications - 7
Citations - 418
Peter O. Krutzik is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Solid-phase synthesis & Binding site. The author has an hindex of 4, co-authored 7 publications receiving 407 citations.
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Increasing rates of reaction: microwave-assisted organic synthesis for combinatorial chemistry.
Journal ArticleDOI
5'-alkyl-benzothiadiazides: a new subgroup of AMPA receptor modulators with improved affinity.
Dean Phillips,Jennifer Sonnenberg,Amy C. Arai,Rishi G. Vaswani,Peter O. Krutzik,Thomas Kleisli,Markus Kessler,Richard Granger,Gary Lynch,A. Richard Chamberlin +9 more
TL;DR: New benzothiadiazides developed with IDRA-21 as lead compound are examined for their potency in modulating AMPA receptor kinetics and offer new insights how receptor Kinetics is linked to particular aspects of receptor--drug interactions.
Journal ArticleDOI
Rapid solid-phase synthesis of DNA-binding pyrrole-imidazole polyamides.
TL;DR: A rapid solid-phase synthesis based on azabenzotriazole (OAt) activation that decreases synthesis time 60% compared to standard benzotrizole (OBt) techniques, without loss of yield or purity is developed.