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Antoine C. G. Egberts
Researcher at Utrecht University
Publications - 283
Citations - 15061
Antoine C. G. Egberts is an academic researcher from Utrecht University. The author has contributed to research in topics: Odds ratio & Population. The author has an hindex of 67, co-authored 279 publications receiving 13896 citations. Previous affiliations of Antoine C. G. Egberts include American Pharmacists Association & Erasmus University Rotterdam.
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Journal ArticleDOI
A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions.
Eugène van Puijenbroek,Andrew Bate,Andrew Bate,Hubert G. M. Leufkens,Marie Lindquist,Roland Orre,Antoine C. G. Egberts +6 more
TL;DR: The objective of this study is to examine the level of concordance of the various estimates to the measure used by the WHO Collaborating Centre for International ADR monitoring, the information component (IC), when applied to the dataset of the Netherlands Pharmacovigilance Foundation Lareb.
Journal ArticleDOI
Frequency of and Risk Factors for Preventable Medication-Related Hospital Admissions in the Netherlands
Anne J. Leendertse,Antoine C. G. Egberts,Lennart J. Stoker,Patricia M. L. A. van den Bemt,Patricia M. L. A. van den Bemt +4 more
TL;DR: The identified risk factors provide a starting point for preventing medication-related hospital admissions, and almost half of these admissions were potentially preventable.
Journal ArticleDOI
The Risk of Cancer in Users of Statins
Matthijs R. Graaf,Annette B. Beiderbeck,Antoine C. G. Egberts,Dick J. Richel,Henk-Jan Guchelaar +4 more
TL;DR: It is suggested that statins may have a protective effect against cancer and are protective when used longer than 4 years or when more than 1350 defined daily doses are taken.
Journal ArticleDOI
Adverse drug events in hospitalized patients: A comparison of doctors, nurses and patients as sources of reports
P.M.L.A. van den Bemt,Antoine C. G. Egberts,A.W. Lenderink,J.M. Verzijl,K.A. Simons,W.S.C.J.M. van der Pol,Hubert G. M. Leufkens +6 more
TL;DR: It is reconfirmed that doctors are the main source for reports of serious and unknown adverse drug events in hospitalized patients, however, patients themselves seem to report more adverse reactions to new drugs (during the daily ward visit), by focusing on patients using new drugs, which might become cost-effective.
Journal ArticleDOI
Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case–control study
Patrick C. Souverein,A Berard,T P van Staa,Cyrus Cooper,Antoine C. G. Egberts,Hubert G. M. Leufkens,Brian R. Walker +6 more
TL;DR: Only a randomised controlled trial of glucocorticoid treatment versus other disease modifying agents is likely to distinguish the importance of the underlying disease activity from its treatment in predicting cardiovascular outcomes.