E
Eugène van Puijenbroek
Researcher at University of Groningen
Publications - 177
Citations - 3773
Eugène van Puijenbroek is an academic researcher from University of Groningen. The author has contributed to research in topics: Pharmacovigilance & Adverse drug reaction. The author has an hindex of 27, co-authored 153 publications receiving 3042 citations. Previous affiliations of Eugène van Puijenbroek include University Medical Center Groningen & Radboud University Nijmegen.
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Journal ArticleDOI
A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions.
Eugène van Puijenbroek,Andrew Bate,Andrew Bate,Hubert G. M. Leufkens,Marie Lindquist,Roland Orre,Antoine C. G. Egberts +6 more
TL;DR: The objective of this study is to examine the level of concordance of the various estimates to the measure used by the WHO Collaborating Centre for International ADR monitoring, the information component (IC), when applied to the dataset of the Netherlands Pharmacovigilance Foundation Lareb.
Journal ArticleDOI
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry
Torbjörn Tomson,Torbjörn Tomson,Dina Battino,Erminio Bonizzoni,John Craig,Dick Lindhout,Emilio Perucca,Anne Sabers,Sanjeev V Thomas,Frank J.E. Vajda,Francesca Faravelli,Chiara Pantaleoni,Elisabeth Robert-Gnansia,Leonor Cabral-Lim,Boštjan Čebular,Alejandro De Marinis,Reetta Kälviäinen,Ketevan Khomeriki,Gordana Kiteva-Trencevska,Silvia Kochen,Martin Kurthen,Gerhard Luef,Meritxell Martinez Ferri,Maja Milovanovic,Karl O. Nakken,Miri Neufeld,Hideyuki Ohtani,Aline Russell,Vladimír Safcák,Bettina Schmitz,Luigi Maria Specchio,Barbara Tettenborn,Eugène van Puijenbroek,Hsiang-Yu Yu,Jana Zárubová,Claus Albretsen,Silje Alvestad,Noémi Becser Andersen,Luisa Antonini,Jens Arentsen,Dag Aurlien,Ismael Barzinji,Juan Luis Becerra Cuñat,Natalia Bohorquez Morera,Martin J. Brodie,Eylert Brodtkorb,Laura Broglio,Elsebeth Bruun Christensen,Petr Bušek,Claudia Cagnetti,Maria Paola Canevini,Astrid Carius,Maria Dolores Castro Vilanova,Michela Cecconi,T.-Y. Chang,Jakob Christensen,Giovanni De Maria,Dieter Dennig,Brenda Diputado,Janne Marit Ertresvåg,Toni Escartin,Dominique Flügel,Birgitte Forsom Sondal,Nicoletta Foschi,Albertina Franza,Katsuyuki Fukushima,Antonio Gambardella,Iñigo Garamendi Ruiz,Helena Gauffin,Pia Gellert,Leif Gjerstad,Lisa Gordon,Katrine Haggag,Imad Halawa,Terttu Heikinheimo-Connell,Tim Hendgen,Zarouhi Hertz,Odo Hildenhagen,Stephanie Hödl,Ineke Hogenesch,Anette Huuse Farmen,Yushi Inoue,Stefan Juhl,Masaaki Kato,Germaine Kenou Van Rijckevorssel,E. Kluck,Hana Krijtová,Eva Kumlien,Angelo Labate,Theresa Lasch,Hans Lindsten,Renata Listonova,Rasmus Lossius,Anders Lundgren,Kristina Malmgren,Iva Marečková,Daniela Marino,Peter Mattsson,Aileen McGonigal,Katarzyna Miesczanleh,Masahiro Mizobuchi,Barbara Mostacci,Birgit Müffelmann,Uden Navn,Anders Nilsson,Bernhard Oehl,Andrea Ortenzi,Judith Osseforth,Aldo Paggi,Eliana Pastor,Birthe Pedersen,Vaiva Petrenaite,Pietro Pignatta,Isabel Pires,Alessandra Pistelli,Jesús Antonio Riuz Gimenez,Raffaele Rocchi,Lone Rodam,Reina Roivainen,Gisela Rytířová,Christian Samsonsen,Gemma Sansa Fayos,Anna Maija Saukkonen,Alma Sikiric,David Sopelana Garay,Bernhard J. Steinhoff,Maria Strandberg,Torleiv Svendsen,Erik Tauboll,Kiyohito Terada,Marina Trivisano,Katherine Turner,Mogens Worm,Elias Zakharia,Elena Zambrelli,Morteza Zarifi-Oskoie +135 more
TL;DR: Risks of major congenital malformation associated with lamotrigine, levetiracetam, and oxcarbazepine were within the range reported in the literature for offspring unexposed to antiepileptic drugs, and rational selection of these drugs is facilitated.
Journal ArticleDOI
The role of data mining in pharmacovigilance.
TL;DR: After a focused review of postapproval drug safety signal detection, the authors explain how the currently used algorithms work and address key questions related to their validation, comparative performance, deployment in naturalistic pharmacovigilance settings, limitations and potential for misuse.
Journal ArticleDOI
Use of measures of disproportionality in pharmacovigilance: three Dutch examples.
TL;DR: Three Dutch examples are described in which a measure of disproportionality is used in quantitative signal detection in pharmacovigilance, and it is concluded that the use of quantitative measures in addition to qualitative analysis is a step forward in signal Detection in pharmacvigilance.
Journal ArticleDOI
On the assessment of adverse drug reactions from spontaneous reporting systems: the influence of under-reporting on odds ratios
Peter G. M. van der Heijden,Eugène van Puijenbroek,Stef van Buuren,Jacques W van der Hofstede +3 more
TL;DR: It is shown that certain under-reporting problems play no role in assessing ADRs from SRSs: the results from the analyses turn out to be biased by some specific under- reporting problems, but not by others.