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Bo Yun Lee
Researcher at Seoul National University
Publications - 2
Citations - 984
Bo Yun Lee is an academic researcher from Seoul National University. The author has contributed to research in topics: Senescence & DNA damage. The author has an hindex of 2, co-authored 2 publications receiving 767 citations.
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Journal ArticleDOI
Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase
Bo Yun Lee,Jung A. Han,Jun Sub Im,Amelia Morrone,Kimberly L. Johung,Edward C. Goodwin,Wim J. Kleijer,Daniel DiMaio,Eun Seong Hwang,Eun Seong Hwang +9 more
TL;DR: It is demonstrated here that SA‐β‐gal activity is expressed from GLB1, the gene encoding lysosomal β‐D‐galactosidase, the activity of which is typically measured at acidic pH 4.5.
Journal ArticleDOI
Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis.
TL;DR: Senescence is associated with ROS accumulation, but apoptosis is caused independently of ROS, as well as p53, p21WAF1, and E2F1.