J
Jung A. Han
Researcher at Seoul National University
Publications - 2
Citations - 912
Jung A. Han is an academic researcher from Seoul National University. The author has contributed to research in topics: Downregulation and upregulation & Gene expression. The author has an hindex of 2, co-authored 2 publications receiving 704 citations.
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Journal ArticleDOI
Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase
Bo Yun Lee,Jung A. Han,Jun Sub Im,Amelia Morrone,Kimberly L. Johung,Edward C. Goodwin,Wim J. Kleijer,Daniel DiMaio,Eun Seong Hwang,Eun Seong Hwang +9 more
TL;DR: It is demonstrated here that SA‐β‐gal activity is expressed from GLB1, the gene encoding lysosomal β‐D‐galactosidase, the activity of which is typically measured at acidic pH 4.5.
Journal ArticleDOI
Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells
Hyung Il Lee,Hwa Jeong Cho,Jung A. Han,So-Young Jang,Kyoung Min Wang,Hyun Tae Kang,Eun Seong Hwang +6 more
TL;DR: In this paper, the effect of nicotinamide at such high dose on gene expression and cellular metabolism has been determined previously, and it was found that levels of O -N-acetylglucosamin(O-GlcNAc)ylated proteins including Sp1 acutely decreased upon treatment of 10 mM nicotinamic acid.