Chandran S Abhinand

TL;DR: This work has developed the first comprehensive map of endothelial cell-specific signaling events of VEGFA/VEGFR2 system pertaining to angiogenesis and believes that this map would serve as a novel platform for reference, integration, and representation and more significantly, the progressive analysis of dynamic features of V EGF signaling in endothelial cells including their cross-talks with other ligand-receptor systems involved inAngiogenesis.

TL;DR: Ritonavir has the highest potency to block SARS-CoV-2 main protease and human TMPRSS2, a host cell factor that aids viral infection that helped viral fusion with the host cell membrane.

TL;DR: An improved update-version of the previous VEGFA signaling network model in endothelial cells is presented as a platform for analysis of cross-talk with these signaling systems.

TL;DR: THL, an Indian ayurvedic herbal formulation made from the dried fruits of three medicinal plants, is used as a herbal drug for the treatment of various diseases, including cancer and the new approach developed to determine the potential efficacy of herbal formulation could be a useful strategy to assess the efficacy of different herbal formulations.

TL;DR: In this paper, gene expression data of xenografts of tumors of bevacizumab-resistant glioblastoma multiforme (GBM) patients, using bioinformatics tools, were reanalyzed to understand the molecular mechanisms of this resistance.