Perumana R. Sudhakaran

TL;DR: This work has developed the first comprehensive map of endothelial cell-specific signaling events of VEGFA/VEGFR2 system pertaining to angiogenesis and believes that this map would serve as a novel platform for reference, integration, and representation and more significantly, the progressive analysis of dynamic features of V EGF signaling in endothelial cells including their cross-talks with other ligand-receptor systems involved inAngiogenesis.

TL;DR: Morphological analysis revealed that human umbilical vein endothelial cells (HUVECs) in culture respond to lactate by switching over to angiogenic phenotype concomitant with upregulation of vascular endothelial growth factor (VEGF) and vascular endotheric growth factor receptor‐2 (VEGFR2) as determined by reverse transcription‐PCR (RT‐PCRs).

TL;DR: The results show that pretreatment with lycopene offers protection against gamma-radiation induced cellular damage and can be developed as an effective radioprotector during radiotherapy.

TL;DR: The present results suggested that the hypolipidaemic effect of dietary fibre involves a decrease in hepatic production of VLDL and further that it varies with the nature of the fibre.

TL;DR: Results indicated that anti-inflammatory effect of curcumin also involves inhibition of the production of MMP-9 in PBMCs.