C
Charles Whittaker
Researcher at Imperial College London
Publications - 129
Citations - 17170
Charles Whittaker is an academic researcher from Imperial College London. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 34, co-authored 94 publications receiving 11232 citations. Previous affiliations of Charles Whittaker include Medical Research Council & Norwich Research Park.
Papers
More filters
Journal ArticleDOI
Estimates of the severity of coronavirus disease 2019: a model-based analysis.
Robert Verity,Lucy C Okell,Ilaria Dorigatti,Peter Winskill,Charles Whittaker,Natsuko Imai,Gina Cuomo-Dannenburg,Hayley A Thompson,Patrick G T Walker,Han Fu,Amy Dighe,Jamie T. Griffin,Marc Baguelin,Sangeeta N. Bhatia,A Boonyasiri,Anne Cori,Zulma M. Cucunubá,Richard G. FitzJohn,Katy A. M. Gaythorpe,W Green,Arran Hamlet,Wes Hinsley,Daniel J Laydon,Gemma Nedjati-Gilani,Steven Riley,Sabine L. van Elsland,Erik M. Volz,Haowei Wang,Y Wang,Xiaoyue Xi,Christl A. Donnelly,Christl A. Donnelly,Azra C. Ghani,Neil M. Ferguson +33 more
TL;DR: These early estimates give an indication of the fatality ratio across the spectrum of COVID-19 disease and show a strong age gradient in risk of death.
Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand
Neil M. Ferguson,Daniel J Laydon,G Nedjati Gilani,Natsuko Imai,Kylie E. C. Ainslie,Marc Baguelin,Sangeeta N. Bhatia,A Boonyasiri,Z Cucunuba Perez,Gina Cuomo-Dannenburg,Amy Dighe,Ilaria Dorigatti,Han Fu,Katy A. M. Gaythorpe,W Green,Arran Hamlet,Wes Hinsley,Lucy C Okell,S Van Elsland,H Thompson,Robert Verity,Erik M. Volz,Haowei Wang,Y Wang,Patrick G T Walker,Caroline E. Walters,Peter Winskill,Charles Whittaker,Christl A. Donnelly,Steven Riley,Azra C. Ghani +30 more
TL;DR: Neil M Ferguson, Daniel Laydon, Gemma Nedjati-Gilani, Natsuko Imai, Kylie Ainslie, Sangeeta Bhatia, Adhiratha Boonyasiri, Zulma Cucunubá, Gina Cuomo-Dannenburg, Amy Dighe, Ilaria Dorigatti, Han Fu, Katy Gaythorpe, Will Green, Arran Hamlet, Wes Hinsley, Lucy C Okell.
Journal ArticleDOI
Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe.
Seth Flaxman,Swapnil Mishra,Axel Gandy,H. Juliette T. Unwin,Thomas A. Mellan,Helen Coupland,Charles Whittaker,Harrison Zhu,Tresnia Berah,Jeffrey W. Eaton,Melodie Monod,Azra C. Ghani,Christl A. Donnelly,Christl A. Donnelly,Steven Riley,Michaela A. C. Vollmer,Neil M. Ferguson,Lucy C Okell,Samir Bhatt +18 more
TL;DR: The results show that major non-pharmaceutical interventions and lockdown in particular have had a large effect on reducing transmission and continued intervention should be considered to keep transmission of SARS-CoV-2 under control.
Journal ArticleDOI
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.
Nuno R. Faria,Thomas A. Mellan,Charles Whittaker,Ingra Morales Claro,Darlan da Silva Candido,Darlan da Silva Candido,Swapnil Mishra,Myuki A E Crispim,Flavia C. S. Sales,Iwona Hawryluk,John T. McCrone,Ruben J.G. Hulswit,Lucas A M Franco,Mariana S. Ramundo,Jaqueline Goes de Jesus,Pamela S Andrade,Thais M. Coletti,Giulia M. Ferreira,Camila A. M. Silva,Erika R. Manuli,Rafael Henrique Moraes Pereira,Pedro S. Peixoto,Moritz U. G. Kraemer,Nelson Gaburo,Cecilia da C. Camilo,Henrique Hoeltgebaum,William Marciel de Souza,Esmenia C. Rocha,Leandro Marques de Souza,Mariana C. Pinho,Leonardo José Tadeu de Araújo,Frederico S V Malta,Aline B. de Lima,Joice do P. Silva,Danielle A G Zauli,Alessandro C. S. Ferreira,Ricardo P Schnekenberg,Daniel J Laydon,Patrick G T Walker,Hannah M. Schlüter,Ana L. P. dos Santos,Maria S. Vidal,Valentina S. Del Caro,Rosinaldo M. F. Filho,Helem M. dos Santos,Renato Santana Aguiar,José Luiz Proença-Módena,Bruce Walker Nelson,James A. Hay,Melodie Monod,Xenia Miscouridou,Helen Coupland,Raphael Sonabend,Michaela A. C. Vollmer,Axel Gandy,Carlos A. Prete,Vitor H. Nascimento,Marc A. Suchard,Thomas A. Bowden,Sergei L Kosakovsky Pond,Chieh-Hsi Wu,Oliver Ratmann,Neil M. Ferguson,Christopher Dye,Nicholas J. Loman,Philippe Lemey,Andrew Rambaut,Nelson Abrahim Fraiji,Maria Perpétuo Socorro Sampaio Carvalho,Oliver G. Pybus,Oliver G. Pybus,Seth Flaxman,Samir Bhatt,Samir Bhatt,Ester Cerdeira Sabino +74 more
TL;DR: In this article, the authors used a two-category dynamical model that integrates genomic and mortality data to estimate that P.1 may be 1.7-to 2.4-fold more transmissible and that previous (non-P.1) infection provides 54 to 79% of the protection against infection with P.
Journal ArticleDOI
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Petra Mlcochova,Steven Kemp,Steven Kemp,Mahesh Shanker Dhar,Guido Papa,Bo Meng,Isabella Ferreira,Rawlings Datir,Dami A. Collier,Dami A. Collier,Anna Albecka,Sujeet Kumar Singh,Rajesh Pandey,Jonathan Brown,Jie Zhou,Niluka Goonawardane,Swapnil Mishra,Charles Whittaker,Thomas A. Mellan,Robin Marwal,Meena Datta,Shantanu Sengupta,Kalaiarasan Ponnusamy,V. S. Radhakrishnan,Adam Abdullahi,Oscar Charles,Partha Chattopadhyay,Priti Devi,Daniela Caputo,Thomas P. Peacock,Chand Wattal,Neeraj Goel,Ambrish Satwik,Raju Vaishya,Meenakshi Agarwal,Antranik Mavousian,Joo-Hyeon Lee,Jessica Bassi,Chiara Silacci-Fegni,Christian Saliba,Dora Pinto,Takashi Irie,Isao Yoshida,William L Hamilton,Kei Sato,Samir Bhatt,Samir Bhatt,Seth Flaxman,Leo C. James,Davide Corti,Luca Piccoli,Wendy S. Barclay,Partha Rakshit,Anurag Agrawal,Ravindra K. Gupta +54 more
TL;DR: The B.617.1.2 spike protein was able to mediate highly efficient syncytium formation that was less sensitive to inhibition by neutralizing antibody, compared with that of wild-type spike as discussed by the authors.