C
Christoph Cremer
Researcher at Heidelberg University
Publications - 329
Citations - 20341
Christoph Cremer is an academic researcher from Heidelberg University. The author has contributed to research in topics: Microscopy & Microscope. The author has an hindex of 63, co-authored 322 publications receiving 19277 citations. Previous affiliations of Christoph Cremer include University of Freiburg & University of Mainz.
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Journal ArticleDOI
Chromosome territories, nuclear architecture and gene regulation in mammalian cells.
TL;DR: The emerging view is that chromosomes are compartmentalized into discrete territories and the location of a gene within a chromosome territory seems to influence its access to the machinery responsible for specific nuclear functions, such as transcription and splicing.
Nuclear architecture and gene regulation in mammalian cells
TL;DR: The emerging view is that chromosomes are compartmentalized into discrete territories, and the location of a gene within a chromosome territory seems to influence its access to the machinery responsible for specific nuclear functions, such as transcription and splicing.
Journal ArticleDOI
Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes
Andreas Bolzer,Gregor Kreth,Irina Solovei,Daniela Koehler,Kaan Saracoglu,Christine Fauth,Stefan C. Müller,Roland Eils,Christoph Cremer,Michael R. Speicher,Thomas Cremer +10 more
TL;DR: Modeling of 3D CT arrangements suggests that cell-type-specific differences in radial CT arrangements are not solely due to geometrical constraints that result from nuclear shape differences, and gene-density-correlated arrangements of higher-order chromatin shared by all human cell types studied so far are found.
Journal ArticleDOI
Aberrations in confocal fluorescence microscopy induced by mismatches in refractive index
TL;DR: In this paper, the effect of refractive-index mismatch on the image acquisition process in confocal fluorescence microscopy is investigated theoretically, taking the vectorial properties of light into account.
Proceedings ArticleDOI
Laterally modulated excitation microscopy: improvement of resolution by using a diffraction grating
TL;DR: In this paper, a diffraction grating was inserted in the illumination beam path at the conjugate object plane (position of the adjustable aperture) and projected through the objective into the object.