C
Christopher Cook
Researcher at National Institutes of Health
Publications - 84
Citations - 3531
Christopher Cook is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Fractional flow reserve & Instantaneous wave-free ratio. The author has an hindex of 19, co-authored 65 publications receiving 2571 citations. Previous affiliations of Christopher Cook include Imperial College London & University College London.
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Journal ArticleDOI
The annual global economic burden of heart failure
TL;DR: The overall economic cost of heart failure in 2012 was estimated at $108 billion per annum, with an aging, rapidly expanding and industrializing global population this value will continue to rise.
Journal ArticleDOI
Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.
Rasha Al-Lamee,Rasha Al-Lamee,David Thompson,David Thompson,Hakim-Moulay Dehbi,Sayan Sen,Sayan Sen,Kare Tang,John R. Davies,Thomas R. Keeble,Michael Mielewczik,Raffi Kaprielian,Iqbal S. Malik,Sukhjinder Nijjer,Ricardo Petraco,Ricardo Petraco,Christopher Cook,Christopher Cook,Yousif Ahmad,Yousif Ahmad,James P. Howard,James P. Howard,Christopher S. Baker,Andrew Sharp,Robert Gerber,Suneel Talwar,Ravi Assomull,Jamil Mayet,Jamil Mayet,Roland Wensel,David Collier,Matthew J. Shun-Shin,Matthew J. Shun-Shin,Simon Thom,Simon Thom,Justin E. Davies,Justin E. Davies,Darrel P. Francis,Darrel P. Francis,Amarjit Sethi,Punit Ramrakha,Rodney A. Foale,Ramzi Khamis,Nearchos Hadjiloizou,Masood Khan,Jaspal S. Kooner,Michael Bellamy,Ghada W. Mikhail,Piers Clifford,Peter O'Kane,Terry Levy,Rosie Swallow +51 more
TL;DR: In patients with medically treated angina and severe coronary stenosis, PCI did not increase exercise time by more than the effect of a placebo procedure, and the primary endpoint was difference in exercise time increment between groups.
Journal ArticleDOI
Evaluation of techniques for the quantification of myocardial scar of differing etiology using cardiac magnetic resonance
Andrew S. Flett,Jonathan Hasleton,Christopher Cook,Derek J. Hausenloy,Giovanni Quarta,Giovanni Quarta,Cono Ariti,Vivek Muthurangu,James C. Moon +8 more
TL;DR: Regardless of the disease under study, the FWHM technique for LGE quantification gives LGE volume mean results similar to manual quantification and is statistically the most reproducible, reducing required sample sizes by up to one-half.
Journal ArticleDOI
Diagnostic accuracy of computed tomography-derived fractional flow reserve a systematic review
Christopher Cook,Ricardo Petraco,Matthew J. Shun-Shin,Yousif Ahmad,Sukhjinder Nijjer,Rasha Al-Lamee,Yuetsu Kikuta,Yasutsugu Shiono,Jamil Mayet,Darrel P. Francis,Sayan Sen,Justin E. Davies +11 more
TL;DR: The diagnostic accuracy of FFR-CT varies markedly across the spectrum of disease and can be used in combination with patient-specific factors to judge when the cost and risk of an invasive angiogram may safely be avoided.
Journal ArticleDOI
The Evolving Future of Instantaneous Wave-Free Ratio and Fractional Flow Reserve
Matthias Götberg,Christopher Cook,Sayan Sen,Sukhjinder Nijjer,Javier Escaned,Justin E. Davies +5 more
TL;DR: How physiological assessment with iFR may advance its application from simply justifying to guiding revascularization is described, outlining developments for both iFR and FFR in new clinical domains beyond the confines of stable angina.