C
Christopher S. Henry
Researcher at Argonne National Laboratory
Publications - 114
Citations - 10141
Christopher S. Henry is an academic researcher from Argonne National Laboratory. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 36, co-authored 103 publications receiving 8224 citations. Previous affiliations of Christopher S. Henry include University of Chicago & Northwestern University.
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Journal ArticleDOI
A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.
Adam M. Feist,Christopher S. Henry,Jennifer L. Reed,Markus Krummenacker,Andrew R. Joyce,Peter D. Karp,Linda J. Broadbelt,Vassily Hatzimanikatis,Bernhard O. Palsson +8 more
TL;DR: An updated genome‐scale reconstruction of the metabolic network in Escherichia coli K‐12 MG1655 with increased scope and computational capability is presented, expected to broaden the spectrum of both basic biology and applied systems biology studies of E. coli metabolism.
Journal ArticleDOI
Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center
Alice R. Wattam,James J. Davis,James J. Davis,Rida Assaf,Sébastien Boisvert,Thomas Brettin,Thomas Brettin,Christopher Bun,Neal Conrad,Neal Conrad,Emily M. Dietrich,Emily M. Dietrich,Terry Disz,Joseph L. Gabbard,Svetlana Gerdes,Christopher S. Henry,Ronald W. Kenyon,Dustin Machi,Chunhong Mao,Eric K. Nordberg,Gary J. Olsen,Daniel E. Murphy-Olson,Robert Olson,Robert Olson,Ross Overbeek,Bruce Parrello,Gordon D. Pusch,Maulik Shukla,Maulik Shukla,Veronika Vonstein,Andrew S. Warren,Fangfang Xia,Fangfang Xia,Hyunseung Yoo,Hyunseung Yoo,Rick Stevens,Rick Stevens +36 more
TL;DR: The Pathosystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center, which provides services for RNA-Seq, variation, model reconstruction and differential expression analysis, all delivered through an updated private workspace.
Journal ArticleDOI
High-throughput generation, optimization and analysis of genome-scale metabolic models
Christopher S. Henry,Matthew DeJongh,Aaron A. Best,Paul M. Frybarger,Ben Linsay,Rick Stevens,Rick Stevens +6 more
TL;DR: The Model SEED is introduced, a web-based resource for high-throughput generation, optimization and analysis of genome-scale metabolic models and introduces techniques to automate nearly every step of this process, taking ∼48 h to reconstruct a metabolic model from an assembled genome sequence.
Journal ArticleDOI
KBase: The United States Department of Energy Systems Biology Knowledgebase.
Adam P. Arkin,Adam P. Arkin,Robert W. Cottingham,Christopher S. Henry,Nomi L. Harris,Rick Stevens,Sergei Maslov,Paramvir S. Dehal,Doreen Ware,Fernando Perez,Shane Canon,Michael W. Sneddon,Matthew L. Henderson,William J. Riehl,Dan Murphy-Olson,Stephen Y. Chan,Roy T. Kamimura,Sunita Kumari,Meghan M Drake,Thomas Brettin,Elizabeth M. Glass,Dylan Chivian,Dan Gunter,David J. Weston,Benjamin H. Allen,Jason K. Baumohl,Aaron A. Best,Benjamin P. Bowen,Steven E. Brenner,Christopher Bun,John-Marc Chandonia,Jer Ming Chia,R. L. Colasanti,Neal Conrad,James J. Davis,Brian H. Davison,Matthew DeJongh,Scott Devoid,Emily M. Dietrich,Inna Dubchak,Janaka N. Edirisinghe,Janaka N. Edirisinghe,Gang Fang,José P. Faria,Paul M. Frybarger,Wolfgang Gerlach,Mark Gerstein,Annette Greiner,James Gurtowski,Holly L. Haun,Fei He,Rashmi Jain,Rashmi Jain,Marcin P. Joachimiak,Kevin P. Keegan,Shinnosuke Kondo,Vivek Kumar,Miriam Land,Folker Meyer,Mark Mills,Pavel S. Novichkov,Taeyun Oh,Taeyun Oh,Gary J. Olsen,Robert Olson,Bruce Parrello,Shiran Pasternak,Erik Pearson,Sarah S. Poon,Gavin Price,Srividya Ramakrishnan,Priya Ranjan,Priya Ranjan,Pamela C. Ronald,Pamela C. Ronald,Michael C. Schatz,Samuel M. D. Seaver,Maulik Shukla,Roman A. Sutormin,Mustafa H Syed,James Thomason,Nathan L. Tintle,Daifeng Wang,Fangfang Xia,Hyunseung Yoo,Shinjae Yoo,Dantong Yu +86 more
TL;DR: Author(s): Arkin, Adam P; Cottingham, Robert W; Henry, Christopher S; Harris, Nomi L; Stevens, Rick L; Maslov, Sergei; Dehal, Paramvir; Ware, Doreen; Perez, Fernando; Canon, Shane; Sneddon, Michael W; Henderson, Matthew L; Riehl, William J; Murphy-Olson, Dan; Chan, Stephen Y; Kamimura, Roy T.
Journal ArticleDOI
Thermodynamics-Based Metabolic Flux Analysis
TL;DR: A significant number of reactions appear to be the first steps in the linear portion of numerous biosynthesis pathways and might be candidates for cell regulation, and it is found that the NAD/NADH and NADP/NadPH ratios maintained in the cell are close to the minimum feasible ratio and maximum feasible ratio, respectively.