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Daniel J. Ledbetter
Researcher at University of Florida
Publications - 9
Citations - 1232
Daniel J. Ledbetter is an academic researcher from University of Florida. The author has contributed to research in topics: Erythropoietin & Congenital diaphragmatic hernia. The author has an hindex of 8, co-authored 9 publications receiving 1204 citations. Previous affiliations of Daniel J. Ledbetter include University of Florida Health Science Center.
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Journal ArticleDOI
Congenital diaphragmatic hernia. Epidemiology and outcome
Max R. Langham,David W. Kays,Daniel J. Ledbetter,Barbara Frentzen,Louie L. Sanford,Douglas S. Richards +5 more
TL;DR: Current data make it clear that CDH represents a major cause of perinatal morbidity and mortality, but no data exist to allow a rigorous comparison of the efficacy of various treatment strategies.
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Detrimental effects of standard medical therapy in congenital diaphragmatic hernia.
TL;DR: This study sets a survival benchmark and strongly suggests the negative effects of hyperventilation and alkalization, and nonstandard ventilatory support of patients with CDH has led to significantly improved survival rates.
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Why is erythropoietin present in human milk? Studies of erythropoietin receptors on enterocytes of human and rat neonates.
TL;DR: Recombinant Epo increases the rate of migration of IEC-6 cells and decreases cytokine-induced apoptosis, and suggests that Epo within human milk has actions on neonate's intestinal function.
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Erythropoietin and the incidence of necrotizing enterocolitis in infants with very low birth weight.
TL;DR: In very low birth weight infants, the incidence of NEC is lower in those who received rEpo, and in the control group the incidence was the same.
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Erythropoietin acts as a trophic factor in neonatal rat intestine
Sandra E. Juul,Daniel J. Ledbetter,Amy E Joyce,Christof Dame,Robert D. Christensen,Yanru Zhao,Vincent G. DeMarco +6 more
TL;DR: REpo is not enterally absorbed in an intact and functional form from the intestines of neonatal rat pups, and enterally dosed rEpo has no erythropoietic effects, however, rEPO acts as a trophic factor in developing rat small bowel whether given enterally or parenterally.