Journal ArticleDOI
Congenital diaphragmatic hernia. Epidemiology and outcome
Max R. Langham,David W. Kays,Daniel J. Ledbetter,Barbara Frentzen,Louie L. Sanford,Douglas S. Richards +5 more
TLDR
Current data make it clear that CDH represents a major cause of perinatal morbidity and mortality, but no data exist to allow a rigorous comparison of the efficacy of various treatment strategies.About:
This article is published in Clinics in Perinatology.The article was published on 1996-12-01. It has received 586 citations till now. The article focuses on the topics: Congenital diaphragmatic hernia & Hernia.read more
Citations
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Journal ArticleDOI
Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update
Kitty G. Snoek,Irwin K M Reiss,Anne Greenough,Irma Capolupo,Berndt Urlesberger,Lucas Wessel,Laurent Storme,Jan Deprest,Thomas Schaible,Arno van Heijst,Dick Tibboel +10 more
TL;DR: Key updated recommendations are planned delivery after a gestational age of 39 weeks in a high-volume tertiary center, conventional mechanical ventilation to be the optimal initial ventilation strategy, and intravenous sildenafil to be considered in CDH patients with severe pulmonary hypertension.
Journal ArticleDOI
Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia
Jacques Jani,Kypros H. Nicolaides,Roberta L. Keller,Alexandra Benachi,C.F.A. Peralta,Romain Favre,O. Moreno,Dick Tibboel,Shlomo Lipitz,Alex J. Eggink,P Vaast,Karel Allegaert,Michael R. Harrison,Jan Deprest +13 more
TL;DR: To assess the value of antenatally determined observed to expected fetal lung area to head circumference ratio (LHR) in the prediction of postnatal survival in isolated, congenital diaphragmatic hernia (CDH), an apples-to- apples comparison study is conducted.
Journal ArticleDOI
Congenital diaphragmatic hernia.
TL;DR: In this article, endothelin-1 (ET1) levels in the first month would be higher in infants with CDH who subsequently expired or were discharged on oxygen (poor outcome), and further hypothesized that ET1 levels would be associated with concurrent severity of PH.
Journal ArticleDOI
Congenital diaphragmatic hernia: A meta-analysis of mortality factors
TL;DR: Prenatal diagnosis of CDH, presence of associated major malformations, and the study population have a major influence on mortality rate.
Journal ArticleDOI
Physiology of Fetal Lung Fluid Clearance and the Effect of Labor
Lucky Jain,Douglas C. Eaton +1 more
TL;DR: The physiologic mechanisms underlying fetal lung fluid absorption are discussed and potential strategies for facilitating neonatal transition are explored.
References
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Journal ArticleDOI
Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type
TL;DR: The purpose of this report is to provide histology‐specific incidence rates within single‐year age groups, stratified by sex and race, among children.
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A prospective study of the outcome for fetuses with diaphragmatic hernia.
TL;DR: The mortality for potentially correctable CDH diagnosed before 24 weeks' gestation is 58%, despite optimal care presently available after birth, despite optimal postnatal care.
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A population-based study of congenital diaphragmatic hernia.
Claudine P. Torfs,Cynthia J. R. Curry,Cynthia J. R. Curry,Thomas F. Bateson,Thomas F. Bateson,Louis H. Honoré,Louis H. Honoré +6 more
TL;DR: The results suggest the need to consider the respective types and subgroups of CDH separately in epidemiologic studies.
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Congenital diaphragmatic hernia: Survival treated with very delayed surgery, spontaneous respiration, and no chest tube☆☆☆
TL;DR: This report suggests that stabilization of the intrauterine to extrauterine transitional circulation combined with a respiratory care strategy that avoids pulmonary overdistension, takes advantage of inherent biological cardiorespiratory mechanics, and very delayed surgery for congenital diaphragmatic hernia results in improved survival and decreases the need for extracorporeal membrane oxygenation (ECMO).
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Experimental study on embryogenesis of congenital diaphragmatic hernia
TL;DR: The present study found that the posthepatic mesenchymal plate plays a cardinal role in the development of the diaphragm and that hypoplasia of the lung bud preceded hypopl Asia of the PHMP in mice with CDH produced by the administration of Nitrofen to their pregnant nothers.