D
Danilo Toni
Researcher at Sapienza University of Rome
Publications - 261
Citations - 15301
Danilo Toni is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Stroke & Thrombolysis. The author has an hindex of 51, co-authored 261 publications receiving 12435 citations. Previous affiliations of Danilo Toni include Policlinico Umberto I.
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Journal ArticleDOI
Guidelines for management of ischaemic stroke and transient ischaemic attack 2008
Peter A. Ringleb,Marie-Germaine Bousser,Gary A. Ford,Philip M.W. Bath,Michael Brainin,Valeria Caso,Álvaro Cervera,Ángel Chamorro,Charlotte Cordonnier,László Csiba,Antoni Dávalos,Hans-Christoph Diener,José M. Ferro,Werner Hacke,Michael G. Hennerici,Markku Kaste,Peter Langhorne,Kennedy R. Lees,Didier Leys,J. Lodder,Hugh S. Markus,Jean-Louis Mas,Heinrich Mattle,Keith W. Muir,Bo Norrving,Victor Obach,Stefano Paolucci,E. Bernd Ringelstein,Peter D. Schellinger,Juhani Sivenius,Skvortsova Vi,Katharina S. Sunnerhagen,Lars Thomassen,Danilo Toni,Rüdiger von Kummer,Nils Wahlgren,Marion F Walker,Joanna M. Wardlaw +37 more
TL;DR: The article covers referral and emergency management, Stroke Unit service, diagnostics, primary and secondary prevention, general stroke treatment, specific treatment including acute management, management of complications, and rehabilitation.
Journal ArticleDOI
Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials
Jonathan Emberson,Kennedy R. Lees,Patrick D. Lyden,Lisa Blackwell,Gregory W. Albers,Erich Bluhmki,Thomas G. Brott,Geoff Cohen,Stephen M. Davis,Geoffrey A. Donnan,James C. Grotta,George Howard,Markku Kaste,Masatoshi Koga,Ruediger von Kummer,Maarten G Lansberg,Richard I. Lindley,Gordon D Murray,Jean-Marc Olivot,Mark W Parsons,Barbara C. Tilley,Danilo Toni,Kazunori Toyoda,Nils Wahlgren,Joanna M. Wardlaw,William Whiteley,Gregory J. del Zoppo,Colin Baigent,Peter Sandercock,Werner Hacke +29 more
TL;DR: In this paper, a pre-specifi ed meta-analysis of individual patient data from 6756 patients in nine randomised trials comparing alteplase with placebo or open control was conducted.
Journal ArticleDOI
Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source
Hans-Christoph Diener,Ralph L. Sacco,J. Donald Easton,Christopher B. Granger,Richard A. Bernstein,Shinichiro Uchiyama,Jörg Kreuzer,Lisa Cronin,Daniel Cotton,Claudia Grauer,Martina Brueckmann,Marina Chernyatina,Geoffrey A. Donnan,José M. Ferro,Martin Grond,Bernd Kallmünzer,Jerzy Krupinski,Byung-Chul Lee,Robin Lemmens,Jaime Masjuan,Odinak Mm,Jeffrey L. Saver,Peter D. Schellinger,Danilo Toni,Kazunori Toyoda +24 more
TL;DR: In patients with a recent history of embolic stroke of undetermined source, dabigatran was not superior to aspirin in preventing recurrent stroke, but there were more clinically relevant nonmajor bleeding events in the dabig atran group.
Journal ArticleDOI
Multivariable Analysis of Outcome Predictors and Adjustment of Main Outcome Results to Baseline Data Profile in Randomized Controlled Trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST)
Nils Wahlgren,Niaz Ahmed,Niclas Eriksson,Franz Aichner,Erich Bluhmki,Antoni Dávalos,Terttu Erilä,Gary A. Ford,Martin Grond,Werner Hacke,Michael G. Hennerici,Markku Kaste,Martin Köhrmann,Vincent Larrue,Kennedy R. Lees,Thomas Machnig,Risto O. Roine,Danilo Toni,Geert Vanhooren +18 more
TL;DR: The unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with those seen in randomized, controlled trials (RCT) when used in routine clinical practice within 3 hours of ischemic stroke onset.
Journal ArticleDOI
Predicting the Risk of Symptomatic Intracerebral Hemorrhage in Ischemic Stroke Treated With Intravenous Alteplase Safe Implementation of Treatments in Stroke (SITS) Symptomatic Intracerebral Hemorrhage Risk Score
Michael V. Mazya,Jose Antonio Egido,Gary A. Ford,Kennedy R. Lees,Robert Mikulik,Danilo Toni,Nils Wahlgren,Niaz Ahmed +7 more
TL;DR: The SITS SICH risk score predicts large cerebral parenchymal hemorrhages associated with severe clinical deterioration, which could aid clinicians to identify patients at high as well as low risk of SICH after intravenous alteplase.