J
Jeffrey L. Saver
Researcher at University of California, Los Angeles
Publications - 804
Citations - 71128
Jeffrey L. Saver is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 116, co-authored 677 publications receiving 59170 citations. Previous affiliations of Jeffrey L. Saver include American Academy of Neurology & Ronald Reagan UCLA Medical Center.
Papers
More filters
Journal ArticleDOI
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Mayank Goyal,Bijoy K Menon,Wim H. van Zwam,Diederik W.J. Dippel,Peter Mitchell,Andrew M. Demchuk,Antoni Dávalos,Charles B. L. M. Majoie,Aad van der Lugt,Maria Angeles De Miquel,Geoffrey A. Donnan,Yvo B.W.E.M. Roos,Alain Bonafe,Reza Jahan,Hans-Christoph Diener,Lucie A. van den Berg,Elad I. Levy,Olvert A. Berkhemer,Vitor Mendes Pereira,Jeremy L. Rempel,Mónica Millán,Stephen M. Davis,Daniel Roy,John Thornton,Luis San Roman,Marc Ribo,Debbie Beumer,Bruce Stouch,Scott Brown,Bruce C.V. Campbell,Robert J. van Oostenbrugge,Jeffrey L. Saver,Michael D. Hill,Tudor G Jovin +33 more
TL;DR: Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment.
Journal ArticleDOI
Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke
Jeffrey L. Saver,Mayank Goyal,Alain Bonafe,Hans-Christoph Diener,Elad I. Levy,Vitor Mendes Pereira,Gregory W. Albers,Christophe Cognard,David J. Cohen,Werner Hacke,Olav Jansen,Tudor G Jovin,Heinrich Mattle,Raul G Nogueira,Adnan H. Siddiqui,Dileep R. Yavagal,Blaise Baxter,Thomas Devlin,Demetrius K. Lopes,Vivek Y. Reddy,Richard du Mesnil de Rochemont,Oliver C. Singer,Reza Jahan +22 more
TL;DR: In patients receiving intravenous t-PA for acute ischemic stroke, thrombectomy with the use of a stent retriever within 6 hours after onset improved functional outcomes at 90 days.
Journal ArticleDOI
Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.
Raul G Nogueira,Ashutosh P Jadhav,Diogo C Haussen,Alain Bonafe,Ronald F. Budzik,Parita Bhuva,Dileep R. Yavagal,Marc Ribo,Christophe Cognard,Ricardo A. Hanel,Cathy A. Sila,Ameer E Hassan,Mónica Millán,Elad I. Levy,Peter Mitchell,Michael Chen,Joey English,Qaisar A. Shah,Frank L. Silver,Vitor Mendes Pereira,Brijesh P Mehta,Blaise Baxter,Michael G. Abraham,Pedro Cardona,Erol Veznedaroglu,Frank R Hellinger,Lei Feng,Jawad F. Kirmani,Demetrius K. Lopes,Brian T. Jankowitz,Michael Frankel,Vincent Costalat,Nirav Vora,Albert J Yoo,Amer M. Malik,Anthony J. Furlan,Marta Rubiera,Amin Aghaebrahim,Jean-Marc Olivot,Wondwossen G Tekle,Ryan K. Shields,Todd Graves,Roger J. Lewis,Wade S. Smith,David S Liebeskind,Jeffrey L. Saver,Tudor G Jovin +46 more
TL;DR: Among patients with acute stroke who had last been known to be well 6 to 24 hours earlier and who had a mismatch between clinical deficit and infarct, outcomes for disability at 90 days were better with thrombectomy plus standard care than with standard care alone.
Journal ArticleDOI
Time Is Brain—Quantified
TL;DR: Quantitative estimates of the pace of neural circuitry loss in human ischemic stroke emphasize the time urgency of stroke care.
Journal ArticleDOI
Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis
Jeffrey L. Saver,Mayank Goyal,Aad van der Lugt,Bijoy K Menon,Charles B. L. M. Majoie,Diederik W.J. Dippel,Bruce C.V. Campbell,Raul G Nogueira,Andrew M. Demchuk,Alejandro Tomasello,Pere Cardona,Thomas Devlin,Donald Frei,Richard du Mesnil de Rochemont,Olvert A. Berkhemer,Tudor G Jovin,Adnan H. Siddiqui,Wim H. van Zwam,Stephen M. Davis,Carlos Castaño,Biggya L. Sapkota,Puck S.S. Fransen,Carlos A. Molina,Robert J. van Oostenbrugge,Ángel Chamorro,Hester F. Lingsma,Frank L. Silver,Geoffrey A. Donnan,Ashfaq Shuaib,Scott Brown,Bruce Stouch,Peter Mitchell,Antoni Dávalos,Yvo B.W.E.M. Roos,Michael D. Hill +34 more
TL;DR: The period in which endovascular thrombectomy is associated with benefit, and the extent to which treatment delay is related to functional outcomes, mortality, and symptomatic intracranial hemorrhage are characterized are characterized.