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Keith W. Muir
Researcher at University of Glasgow
Publications - 347
Citations - 23410
Keith W. Muir is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Modified Rankin Scale. The author has an hindex of 64, co-authored 347 publications receiving 19103 citations. Previous affiliations of Keith W. Muir include Robertson Centre for Biostatistics & University of Edinburgh.
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Journal ArticleDOI
Guidelines for management of ischaemic stroke and transient ischaemic attack 2008
Peter A. Ringleb,Marie-Germaine Bousser,Gary A. Ford,Philip M.W. Bath,Michael Brainin,Valeria Caso,Álvaro Cervera,Ángel Chamorro,Charlotte Cordonnier,László Csiba,Antoni Dávalos,Hans-Christoph Diener,José M. Ferro,Werner Hacke,Michael G. Hennerici,Markku Kaste,Peter Langhorne,Kennedy R. Lees,Didier Leys,J. Lodder,Hugh S. Markus,Jean-Louis Mas,Heinrich Mattle,Keith W. Muir,Bo Norrving,Victor Obach,Stefano Paolucci,E. Bernd Ringelstein,Peter D. Schellinger,Juhani Sivenius,Skvortsova Vi,Katharina S. Sunnerhagen,Lars Thomassen,Danilo Toni,Rüdiger von Kummer,Nils Wahlgren,Marion F Walker,Joanna M. Wardlaw +37 more
TL;DR: The article covers referral and emergency management, Stroke Unit service, diagnostics, primary and secondary prevention, general stroke treatment, specific treatment including acute management, management of complications, and rehabilitation.
Journal ArticleDOI
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.
Stephen M. Davis,Geoffrey A. Donnan,Mark W Parsons,Christopher R Levi,Kenneth Butcher,André Peeters,P. Alan Barber,Christopher F. Bladin,Deidre A. De Silva,Graham Byrnes,Jonathan B. Chalk,John N. Fink,Thomas E. Kimber,David Schultz,Peter J. Hand,Judith Frayne,Graeme J. Hankey,Keith W. Muir,Richard P. Gerraty,Brian M. Tress,Patricia Desmond +20 more
TL;DR: Alteplase was non-significantly associated with lower infarct growth and significantly associated with increased reperfusion in patients who had mismatch, and phase III trials beyond 3 h after treatment are warranted.
Journal Article
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial
Stephen M. Davis,Geoffrey A. Donnan,Mark W Parsons,Christopher R Levi,Kenneth Butcher,André Peeters,Peter Barber,Christopher F. Bladin,Deidre A De Silva,Graham Byrnes,Jonathan B Chalk,John N. Fink,Thomas E. Kimber,David Schultz,Peter J. Hand,Judith Frayne,Graeme J. Hankey,Keith W. Muir,Richard P. Gerraty,Brian M. Tress,Patricia Desmond +20 more
TL;DR: In this paper, Alteplase was shown to promote reperfusion and attenuate infarct growth in patients who have a mismatch in perfusion-weighted MRI (PWI) and diffusion weighted MRI (DWI).
Journal ArticleDOI
MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset
Götz Thomalla,Claus Z. Simonsen,Florent Boutitie,Grethe Andersen,Yves Berthezène,Bastian Cheng,Bharath Kumar Cheripelli,Tae-Hee Cho,Franz Fazekas,Jens Fiehler,Ian Ford,Ivana Galinovic,Susanne Gellissen,Amir Golsari,Johannes Gregori,Matthias Günther,Jorge Guibernau,Karl Georg Häusler,M. Hennerici,André Kemmling,Jacob Marstrand,Boris Modrau,Lars Neeb,Natalia Pérez de la Ossa,Josep Puig,Peter Ringleb,Pascal Roy,Enno Scheel,Wouter J. Schonewille,Joaquín Serena,Stefan Sunaert,Kersten Villringer,Anke Wouters,Vincent Thijs,Martin Ebinger,Matthias Endres,Jochen B. Fiebach,Robin Lemmens,Keith W. Muir,N. Nighoghossian,Salvador Pedraza,Christian Gerloff +41 more
TL;DR: In patients with acute stroke with an unknown time of onset, intravenous alteplase guided by a mismatch between diffusion‐weighted imaging and FLAIR in the region of ischemia resulted in a significantly better functional outcome and numerically more intracranial hemorrhages than placebo at 90 days.
Journal ArticleDOI
Improving the Assessment of Outcomes in Stroke: Use of a Structured Interview to Assign Grades on the Modified Rankin Scale
J T Lindsay Wilson,Asha Hareendran,Marie Grant,Tracey Baird,Ursula G.R. Schulz,Keith W. Muir,Ian Bone +6 more
TL;DR: An exercise to validate the assessment of the mRS over the telephone by nonphysician interviewers using an analogously structured interview for the modified Rankin Scale.