D
Dapeng Xu
Researcher at Xiamen University
Publications - 62
Citations - 1635
Dapeng Xu is an academic researcher from Xiamen University. The author has contributed to research in topics: Phylogenetic tree & Oligotrich. The author has an hindex of 19, co-authored 54 publications receiving 1308 citations. Previous affiliations of Dapeng Xu include North Carolina Central University & Ocean University of China.
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Inhibition of Ras for cancer treatment: the search continues
TL;DR: An overview of past and ongoing strategies to inhibit oncogenic Ras in cancer is presented and genome-wide unbiased genetic screens have identified novel directions for future anti-Ras drug discovery.
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The All-Data-Based Evolutionary Hypothesis of Ciliated Protists with a Revised Classification of the Phylum Ciliophora (Eukaryota, Alveolata).
Feng Gao,Alan Warren,Qianqian Zhang,Jun Gong,Miao Miao,Ping Sun,Dapeng Xu,Jie Huang,Zhenzhen Yi,Weibo Song +9 more
TL;DR: The molecular dataset was expanded with representatives from 55 orders and all major lineages and the monophyly of classes Phyllopharyngea, Karyorelictea, Armophorea, Prostomatea, Plagiopylea, Colpodea and Heterotrichea are confirmed.
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The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells
Dapeng Xu,Stephen A. Allsop,Sam M. Witherspoon,Jared L. Snider,Jen Jen Yeh,James J. Fiordalisi,Catherine D. White,Daniel Williams,Adrienne D. Cox,Antonio T. Baines +9 more
TL;DR: It is shown that Pim-1 is required for PDAC cell growth, invasion and radioresistance downstream of oncogenic K-Ras, and this work helps elucidate the role of PIM-1 in PDAC growth transformation and validate Pin-1 kinase as a potential molecular marker for mutated K- Ras activity.
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Microbial Eukaryote Diversity and Activity in the Water Column of the South China Sea Based on DNA and RNA High Throughput Sequencing.
TL;DR: Light is shed on the diversity and activity of microbial eukaryotes in the water column of a tropical oligotrophic ocean and their potential contributions in the downward transportation of organic material from the surface ocean to the deep via the biological pump.
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Genetic Identities of Cryptic Species in the Strombidium stylifer/apolatum/oculatum Cluster, Including a Description of Strombidium rassoulzadegani n. sp.
TL;DR: To assess diversity among cryptic species of the ciliate genus Strombidium, small subunit ribosomal DNA gene (SSU‐rDNA) was characterized from several lineages that had been identified previously as distinct based on the internal transcribed spacer regions of the rDNA locus.