D
Dong Gun Lee
Researcher at Kyungpook National University
Publications - 185
Citations - 8217
Dong Gun Lee is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Candida albicans & Apoptosis. The author has an hindex of 46, co-authored 183 publications receiving 7055 citations. Previous affiliations of Dong Gun Lee include Chosun University & UPRRP College of Natural Sciences.
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Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila.
Ji-Hwan Ryu,Sung-Hee Kim,Hyo-Young Lee,Hyo-Young Lee,Jin Young Bai,Young-Do Nam,Jin-Woo Bae,Dong Gun Lee,Seung Chul Shin,Seung Chul Shin,Eun-Mi Ha,Won-Jae Lee +11 more
TL;DR: It is shown that the intestinal homeobox gene Caudal regulates the commensal-gut mutualism by repressing nuclear factor kappa B–dependent antimicrobial peptide genes, and reveals that a specific genetic deficiency within a host can profoundly influence the gut commensAL microbial community and host physiology.
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Antifungal activity and mode of action of silver nano-particles on Candida albicans
Keuk Jun Kim,Woo Sang Sung,Bo Kyoung Suh,Seok-Ki Moon,Jong Soo Choi,Jong Guk Kim,Dong Gun Lee +6 more
TL;DR: The results suggest nano-Ag may exert an antifungal activity by disrupting the structure of the cell membrane and inhibiting the normal budding process due to the destruction of the membrane integrity.
Journal Article
Antifungal effect of silver nanoparticles on dermatophytes.
TL;DR: The present study indicates nano-Ag may have considerable antifungal activity, deserving further investigation for clinical applications.
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Synergistic effects between silver nanoparticles and antibiotics and the mechanisms involved.
TL;DR: Silver nanoparticles have potential as a combination therapeutic agent for the treatment of infectious diseases by bacteria and were found to have antibacterial effects and synergistic activities.
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Silver nanoparticles induce apoptotic cell death in Candida albicans through the increase of hydroxyl radicals.
TL;DR: The results indicate that silver nanoparticles possess antifungal effects with apoptotic features and suggest that the hydroxyl radicals generated bysilver nanoparticles have a significant role in mitochondrial dysfunctional apoptosis.