Journal ArticleDOI
Antifungal activity and mode of action of silver nano-particles on Candida albicans
Keuk Jun Kim,Woo Sang Sung,Bo Kyoung Suh,Seok-Ki Moon,Jong Soo Choi,Jong Guk Kim,Dong Gun Lee +6 more
TLDR
The results suggest nano-Ag may exert an antifungal activity by disrupting the structure of the cell membrane and inhibiting the normal budding process due to the destruction of the membrane integrity.Abstract:
In this study, the antifungal effects of silver nano-particles (nano-Ag) and their mode of action were investigated. Nano-Ag showed antifungal effects on fungi tested with low hemolytic effects against human erythrocytes. To elucidate the antifungal mode of action of nano-Ag, flow cytometry analysis, a glucose-release test, transmission electron microscopy (TEM) and the change in membrane dynamics using 1,6-diphenyl-1,3,5-hexatriene (DPH), as a plasma membrane probe, were performed with Candida albicans. The results suggest nano-Ag may exert an antifungal activity by disrupting the structure of the cell membrane and inhibiting the normal budding process due to the destruction of the membrane integrity. The present study indicates nano-Ag has considerable antifungal activity, deserving further investigation for clinical applications.read more
Citations
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A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment
TL;DR: A review of the antibacterial effects of silver nanomaterials, including proposed antibacterial mechanisms and possible toxicity to higher organisms, is presented in this paper, where the authors suggest that further research is warranted given the already widespread and rapidly growing use of silver nanoparticles.
Journal ArticleDOI
Surface modification of inorganic nanoparticles for development of organic–inorganic nanocomposites—A review
TL;DR: In this paper, the surface of inorganic nanoparticles is modified to improve the interfacial interactions between the inorganic particles and the polymer matrix, which improves the properties of polymeric composites.
Journal ArticleDOI
Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors
TL;DR: Several applications of nanomaterials in food packaging and food safety are reviewed, including polymer/clay nanocomposites as high barrier packaging materials, silver nanoparticles as potent antimicrobial agents, and nanosensors and nanomMaterial-based assays for the detection of food-relevant analytes.
Journal ArticleDOI
Antibacterial activity and mechanism of silver nanoparticles on Escherichia coli.
TL;DR: The combined results suggested that SNPs may damage the structure of bacterial cell membrane and depress the activity of some membranous enzymes, which cause E. coli bacteria to die eventually.
Journal ArticleDOI
Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
TL;DR: The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.
References
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Journal ArticleDOI
Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria
Ivan Sondi,Branka Salopek-Sondi +1 more
TL;DR: These nontoxic nanomaterials, which can be prepared in a simple and cost-effective manner, may be suitable for the formulation of new types of bactericidal materials.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Luminescent quantum dots for multiplexed biological detection and imaging.
Warren C. W. Chan,Dustin J. Maxwell,Xiaohu Gao,Robert E. Bailey,Ming-Yong Han,Shuming Nie,Shuming Nie +6 more
TL;DR: This work has shown how the emission wavelength of quantum-dot nanocrystals can be continuously tuned by changing the particle size, and a single light source can be used for simultaneous excitation of all different-sized dots.
Journal ArticleDOI
New insights on trehalose: a multifunctional molecule
TL;DR: This sugar is present in a wide variety of organisms, including bacteria, yeast, fungi, insects, invertebrates, and lower and higher plants, where it may serve as a source of energy and carbon and as a signaling molecule to direct or control certain metabolic pathways or even to affect growth.
Journal ArticleDOI
Bacterial silver resistance: molecular biology and uses and misuses of silver compounds
TL;DR: Resistance to silver compounds as determined by bacterial plasmids and genes has been defined by molecular genetics and the use of molecular epidemiological tools will establish the range and diversity of such resistance systems in clinical and non-clinical sources.
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Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria
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