D
Drew A. Torigian
Researcher at University of Pennsylvania
Publications - 357
Citations - 12998
Drew A. Torigian is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Positron emission tomography & Standardized uptake value. The author has an hindex of 48, co-authored 329 publications receiving 11021 citations. Previous affiliations of Drew A. Torigian include Hospital of the University of Pennsylvania & Children's Hospital of Philadelphia.
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Journal ArticleDOI
CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
Gregory L. Beatty,Elena G. Chiorean,Matthew P. Fishman,Babak Saboury,Ursina R. Teitelbaum,Weijing Sun,Richard D. Huhn,Wenru Song,Dongguang Li,Leslie L. Sharp,Drew A. Torigian,Peter J. O'Dwyer,Robert H. Vonderheide +12 more
TL;DR: These findings demonstrate a CD40-dependent mechanism for targeting tumor stroma in the treatment of cancer and demonstrate that cancer immune surveillance does not necessarily depend on therapy-induced T cells; rather, it is shown that tumor regression required macrophages but not T cells or gemcitabine.
Journal ArticleDOI
The national lung screening trial: Overview and study design
Constantine A. Gatsonis,Denise R. Aberle,Christine D. Berg,William C. Black,Timothy R. Church,Richard M. Fagerstrom,Barbara Galen,Ilana F. Gareen,Jonathan Goldin,John K. Gohagan,Bruce J. Hillman,Carl Jaffe,Barnett S. Kramer,David A. Lynch,Pamela M. Marcus,Mitchell D. Schnall,Daniel C. Sullivan,D. Sullivan,Carl J. Zylak,Chris H. Cagnon,Dianna D. Cody,Glenn Fletcher,Michael J. Flynn,Philip F. Judy,Randell Kruger,Frederick J. Larke,Michael F. McNitt-Gray,Thomas Payne,J. Anthony Seibert,Xizeng Wu,Gerald F. Abbott,Judith K. Amorosa,Richard G. Barr,Phillip M. Boiselle,Caroline Chiles,Robert A. Clark,Lynn Coppage,Robert Falk,Elliot K. Fishman,David Gemmel,Jonathan G. Goldin,Eric T. Goodman,Eric M. Hart,Todd R. Hazelton,Elizabeth Johnson,Ella A. Kazerooni,Barbara L. McComb,Geoffrey McLennan,Reginald F. Munden,James G. Ravenel,Michael Sullivan,Stephen J. Swensen,Drew A. Torigian,Kay H. Vydareny,John A. Worrell,Peter Balkin,Mona Fouad,Matthew T. Freedman,Kavita Garg,Edward P. Gelmann,David S. Gierada,William G. Hocking,Subbarao Inampudi,Claudine Isaacs,Paul A. Kvale,Howard Mann,William Manor,Hrudaya Nath,Douglas J. Reding,David L. Spizarny,Diane C. Strollo,John Waltz,Mei Hsiu Chen,Fenghai Duan,Grant Izmirilian,Paul F. Pinsky,Philip C. Prorok,Anthony B. Miller,Martin J. Edelman,William K. Evans,Robert S. Fontana,Mitchell Machtay,Kenneth W. Clark,Kathy L. Clingan,Melissa Ford,Guillermo Marquez,Steven M. Moore,Peter Ohan,Thomas J. Payne,Steven Peace,Jennifer Rosenbaum,Richard Barr,William C. Black,Drew Torigian,Kay Vydareny,John Worrell,Robert C. Young,David S. Alberts,David DeMets,Peter Greenwald,Paula M. Jacobs,Theresa C. McLoud,David P. Naidich,James L. Tatum,Edward A. Sausville,Wylie Burke,Gene L. Colice,Brenda Edwards,Scott Emerson,John Fletcher,Sylvan Green,Russell Harris,Jeffrey S. Klein,Edward L. Korn,Robert Mayer,Joe V. Selby,David W. Sturges,Bruce W. Turnbull,Thomas J. Watson,Stephen Baylin,Neil E. Caporaso,Philip Dennis,Steve Dubinett,Wilbur A. Franklin,William E. Grizzle,Fred R. Hirsch,Pierre P. Massion,Kathy McKeeta-Frobeck,John D. Minna,Edward F. Patz,Margaret R. Spitz,Christine B. Berg,Donald Corle,Ping Hu,Grant Izmirlian,Jennifer Gaegler,Susan Hoffman,Charles Jackson,Erin Lange,Evanthia Papadopoulos,Constantine Gatsonis,Iiana Gareen,Charles Apgar,Anna Boyle,Tom Caldwell,Nancy Fredericks,Deborah Harbison,Donna Hartfeil,Sharon Jones,Steve King,Irene Mahon,Rosa M. Medina,Cindy Masiejczyk,Peter Zamora,Hank Brastater,Vish Iyer,Jincy George,Dinakar Gopalakrishnan,Patricia Blair,Michael Bradley,Cheryl Crozier,Maria Oh,Nicole Spiese,Chris Steward,Mary Kelly-Truran,Tess Thompson,Erin Cunningham,Anthony Levering,Kathleen McMurtrie,Michael Nahill,Sharlene Snowden,Kesha Smith,Fraser Wilton,Timothy Welsh,Rex Welsh,Wendell Christie,Stephanie Clabo,Roberta Clune,Natalie Cunningham,Jamie Downs,Lindsey Dymond,Julianne Falcone,Shani Harris,Pamela Harvey,Jane Hill,Laura Hill,Donna Letizia,Kendrick Looney,Hugh McGinley,Angelee Mean,Marcella Moore,Ryan Norton,Valentina Ortico,Sophia Sabina,Robert Sole,Jo Ann Stetz,Arnold Ssali,John Stubblefield,Tina Taylor,Shovonna White,Bo Lu,Amanda M. Adams,Sarah Baum,Meridith Blevins,Patricia Fox,Vincent Girardi,Jeremy Gorelick,Edward Hunt,Quentin McMullen,Karthikeyan Meganathan,Regina Rendas-Baum,Jo Rean D. Sicks,Bradley S. Snyder,Melanie Yeh,Maryann Duggan,Cheryl Souza,Jack Cahill,Brenda K. Brewer,Barbara O'Brien,Gillian Devereux,Melissa S. Fritz,Miriam Galbraith,Judith Harkins,Kristen Keating,Kirk Midkiff,Usha Singh,Thea Palmer Zimmerman,Nancy Payte,Helen Price,Clifford Caughman,Ramachandra Chanapatna,Mike Florzyk,Annabelle Lee,Alan Morgan,Jennifer Yang,L. Ellen Martinusen,June McSwain,Rhonda Rosario,Jagdish Singh,R. Adam DeBaugh,Sharan L. Campleman,Mary Mesnard,Lawrence R. Ragard,Terry Lewis,Lois M. Roberts,Vijayasri Narayanaswami,Vanessa Ralda,William Lake,Thomas Riley,Jonathan B. Clapp,Joe Austin,Brian Irons,Fang F. Xu,Gordon C. Jones,Michael Young,Andrew Goodman,Crissy Kibic,Patricia Sheridan,Nancy Kadish,Denise Moline,Rachel Phillips,Michele Adkinson,David Creed,Tammy DeCoste,Debbie Gembala,Sally Hurst,Elizabeth King,Joy Knowles,Pamela McBride,Patricia Pangburn,Judy Preston,Karen Stokes,Patricia Tesch,Susan Wenmoth,Linda Galocy,Deanna Mandley,Gail Orvis,Alphonso Dial,Letitia Clark,Lawrence F Cohen,Joanne Gerber,Carlos Jamis-Dow,Erini Makariou,Edward Reed Smith,Amy Garrett,Colleen McGuire,Sarah Neff,Tara Riley,Sara Cantrell,Glynis Marsh,Chrispina Wray,Baigalmaa Yondonsambuu,Ulander Giles,Morgan Ford,Venus Brown,Amy Lita Evangelista,Tiffanie Hammond,Jillian Nickel,Michael Brangan,Michele Lee,Cindy Lin,Elanor Adkins,George Armah,Christopher Blue,Venetia Cooke,Natalie Gray,Marianna Gustitis,Lakisha Hawkins,Grace Isaacs,Mimi Kim,Malcolm King,Kanya Kumbalasiri,Robin Laura,Kelly McDaniel,Alem Mulugeta,Leroy Riley,Shane Sorrell,William Thomas,Lisa Woodard,Christine Cole Johnson,Martin Tammemagi,David Spizarny,Carl J. Zylak,Michael J. Flynn,Gordon Jacob Sen,Steadman Sankey,Lonni Schultz,Kalin Albertsen,Karen Broski,Gena Kucera,Kathleen Poler,Cheryl Spoutz-Ryan,Dawn Thomas,Evangeline Griesemer,Bonnie Kwit,Patricia Fantuz,Beth McLellan,Dawn Simmons,Yasmeen Hafeez,Noel Maddy,La Tonja Davis,Rodkise Estell,Susanne Kozakowski,Jennifer Rowe,Merideth Stanley,Xiuli Zhang,Mary Ellen Frebes,Margaret Paquette,Mirjana Tecmire,Laura Young,Deborah Greene,Cynthia Hill,Kathleen Young,Karen Bellware,Kay Bohn,Nancy Caird,Helen Fink,Sandra Fiarman,Melissa Houston,Ann Jolly,Carissa Krzeczkowski,Cynthia Mack,Lakeshia Murray,Anna Nanovski,Debra Rempinski,Heather Tumberlinson,Debbie William,Eleace Eldridge-Smith,Vanessa Graves,Nora Szabo,John Crump,Randall Kruger,Robert T. Greenlee,Karen Lappe,Deb Multerer,Denise Kriescher,Amy Vieth,Sheila Wein,Dawn Fuehrer,Christine Gjertson,June Krebsbach,Craig Kuhlka,Karen Luttrop,Judy Netzer,Jean Wegner,Virginia Fischer,Kay Mathiesen-Viergutz,Karen Kofka,Nikki Jablonsky,Brooke Johnson,Terrie Kitchner,Lin Mueller,Amy Rueth,Shirley Wachholz,Kari Bohman,Marilyn Bruger,Kari Ranae Kramer,Katie Kuenhold,Camille Mueller,Cathy Mueller,Laura Multerer,Sue Zahradka,Janan Alkilidar,Nandita Bhattacharjee,Christopher J. Cangelosi,Robert A. Carlson,Alon Coppens,Margo Cousins,Barry Edelstein,Kristin M. Gerndt,Jeffrey Heffernon,Thomas D. Hinke,Mark Hinson,Lawrence G. Hutchins,Kristin Lieberman,Gerald M. Mulligan,Emmanuel Omoba,Todd Risa,John Sheflin,Tim Swan,John J. Warner,Alan Williams,Lance A. Yokochi,Roy Adaniya,Karen Glanz,James J. Navin,Vicki Shambaugh,Frank Tabrah,Bradley Willcox,Paulette Williams,Qimei He,Victoria Jenkins,Kathleen Bow,Jean Tsukamoto,Shirleen Hyun,Edward M. Brown,Howard Morrow,Kimberly Stryker,Helene Shiratori,Peggy Lau,Bonna Au,Wendy Francis,Liz Bolan,Jazman Brooke,Marilyn Calulot,Victoria Chun,Kathryn Rabanal,Joy Tani,Cheryl M. Lewis,June Morfit,Amy Brunst,Louisa Turner,Gladys Hino,Anne Chung,Constance Elbon-Copp,William Huynh,Myrle Johnson,Esther Nakano,Lilian Villaruz,Mona N. Fouad,William C. Bailey,Robert I. Garver,Dale Brawner,Ian Malcomb,Desiree E. Morgan,Patricia C. Sanders,Arthur Sandy,Martin L. Schwartz,Satinder Singh,Mark T. Dransfield,Darlene Higgins,Alisha Moore,Aras Acemgil,Tony Blake,Jing Lee,Sam Quattlebaum,Julie Schach,Tawny Martin,Rekha Khatri,Wahied Gendi,Beverly Powell,Carolyn M. Johnson,Julie Sears,Shari Jordan,Vicki Prayer,Carole Walker,Mel Johnson,Joanice Thompson,E. David Crawford,Paul A. Bunn,Eduard J. Gamito,Sheryl L. Ogden,Shannon M. Pretzel,Lauren J. Ramsay,Carol Vaughn,Cheri Whiton,Donna Sammons,Laura Springhetti,Sally Tenorio,Nichoie Cadez,Sydney Laster,Sydney Laster,Colin O'Donnell,Joe Hughes,Jennifer Garcia Livingston,Garry Morrison,Wendy Moss,Merri Mullennix,Marissa Peters,Hakan Sahin,Meredith Slear,Mike Burek,Carolyn Hill,Emily Jewitt,Ryan Pena,Eda Ordonez,Gina Sammons,Jhenny Hernandez,Alejandra Reyes,Analisa Somoza,Martin M. Oken,Beborah Bay,Kevin Edelman,Tammy Fox,Scott Gaerte,Karla Myra-Bloom,Michael Plunkett,Frederick Olson,Paul Rust,L. A. Schneider,Beverly Trombley,Thomas Vahey,Ann Bangerter,Terri David-Schlegel,Donna DesMarais,Sue Frederickson,Mindy S. Geisser,Natalya Portnov,Greg M. Silverman,Frank Stahan,Simone Vuong,Gavin D. Watt,Joe Woodside,Aaron Zirbes,Sophie Breer,Cheri Haselhuhn,Cathy Longden,Candace Mueller,Marianne Rice,Deb Warren,Susan Collins,Stephanie Levi,Janet Manual,Lea Matous,Phyllis Olsson,Susan M. Peterson,Christopher M. Rogers,Mary Lynn Steele,Patty Beckmann,Linda Jurjans,Shirley Terrian,Sally Fraki,Martha Fronheiser,Linda Heinrichs,Deb Kirby,Jackie Seivert,Carol Steinberg,Marge Watry,Karen Boyle,Andrew Burnside,Renae Kiffmeyer,Wendy Mosiman,Angie Bailey,Pamela Byrnes,Laura Stark,Mary Weston,Dawn Whistler,Jill E. Cordes,Deb Engelhard,Jackie Becker,Peggy Bradley,James Fisher,Heather McLaughlin,Ana Maria Mendez,Deanna L. Miller,Rosalie Ronan,Brad Siga,Joel L. Weissfeld,Mark B. Salerno,Jeffrey G. Schragin,Diane C. Strollo,Thomas E. Warfel,Patrick W. Wolfe,Dominick A. Antico,Matthew T. Bee,Donald F. Bittner,William T. Corey,Robert A. Hawkins,William T. Herbick,Mukesh F. Karwat,Kevin J. Leonard,Constantine N. Petrochko,Scott F. Pickering,Paul E. Smart,Phyllis J. Walters,Jane A. Zehner,Karen Augustine,Sue Misko,Monica Richel,Mary Alyce Riley,Linda Warren,Kathy McDonough,Beverly Rozanok,Juanita Helms,Peggy Olson,Steve D. Uttecht,Mike Wirth,Roni Atkins,Lisa Clement,Deb Gurtner,Laura Jones,Saundra S. Buys,Ralph Drosten,Kathleen A. Murray,Kenneth Nowers,Peter Jenkins,Dave Tripp,Gabe Herron,Eduard Van Stam,Julie Varner,Karen O’Toole,Cassie Olson,Derek Omori,Adriane Andersen,Neil Argyle,Jennifer Avrin,Jennifer Bacon,Mark Broschinsky,Chani Montalbo,Kimberly Nolan,Anne Randall,Karen Schleip,Scott J. Sheltra,Roger Tischner,Christopher Toyn,Kyle Turner,Brianne Whittaker,Eddy Wicklander,Jacob Wolf,Cherie Baiton,Briar Doi,Jeff Childs,Lisa H. Gren,Darcy Watson,Tony Jones,Bruce Neilson,Hector Ahumada,Hassan Bourija,Christine Brown,Barbara Ferris,Leanne Hadfield,Kylee Hansen,Jeffrey Koford,Sally Anne Kopesec,Amy Lloyd,Mindy Lofthouse,Saeed Matinkhah,Virginia May,Shanna Nichols,Alesis Nieves,Misty Oviatt,Nicole Richardson,Angela Lee Rowley,Ellen Sandberg,Shauna Dave Scholl,Lyn Seguin,David Shea,Suzanne Smith,Patricia Ann Street,Mareie Walters,Ralph Weiben,Lynly Wilcox,Ray Zisumbo,Thomas M. Beck,John S. Waltz,Shane Ball,Todd B. Burt,Elaine N. Daniel,Quinn A. DeMordaunt,Michael T. Fisher,Michael A. Fuchs,Bruce E. Hubler,Chris J. Jennings,Richard H. Lane,Craig E. Leymaster,Loren C. Macey,Steven V. Marx,James R. Maxwell,Brent B. Nelson,Jeff Fairbanks,Bonita Wohlers,Jill Heinz,Kathy Berreth,Randy Marshall,Jerry Brekke,K.E. Jones,Amber Barrow,Douglas Bashford,Barry Clot,Troy Cook,Leslie Dobson,Andrea Hamilton-Foss,William M. Hanson,Jan E. Hyder,Cindy Lewis-Burke,Stacey Mitchell,Marlea Osterhout,Karen Patella,Phillip Peterson,Sandra Schornak-Curtis,Lisa Sirianni,Larry Stoller,Korinna Vigeant,Cheryl Whistle,Jeff Yates,Gerald L. Andriole,D. Claire Anderson,Sanjeev Bhalla,Andrew J. Bierhals,Jason Bronfman,Harvey Glazer,Fernando R. Gutierrez,Guillermo Geisse,Lawrence M. Kotner,Cylen Javidan-Nejad,Kianoush Rezai,Stuart S. Sagel,J W Semenkovich,Marilyn J. Siegel,Dallas Sorrel,Pamela K. Woodard,David Engelhart,Robin Haverman,Angela Campbell,Vivien Gardner,Danielle Gherardini,Lynn Hoese,Ruth Holdener,Louise Ledbetter,Patricia Nieters,Cynthia Reiners,Jeanine Wade,Mary Wiseman,Patricia Rueweler,Rochelle Williams,David Chi,Tim Budd,Janise Webb,Celia Stolin,Kathy Garrett,Elizabeth Fleming,Elaine Freesmeier,Jennifer Frye,Deborah Graham,Helen Kaemmerer,Jo Ann Nevilles,Kathy Taylor,James Blaine,Kenneth W. Clark,D S Gierada,Paul Koppel,David R. Maffitt,Stephen M. Moore,Joan Molton,Stanley R. Phillips,Fred W. Prior,Mary A. Wolfsberger,Angela Cosas,Sooah Kim,Miyoung Kim,Yuting Liang,Thomas K. Pilgram,Amy Haas,Divine Hartwell,Dana Roeshe,Adelheid Lowery,Shelly Meese,Kate Naughton,Roberta Yoffie,Kirk E. Smith,Richard M. Schwartzstein,Pei Jan P Lin,Tim A. Parritt,Elisabeth A. Grady,Lisa Damon,Sharon Gard,Robin Griggs,Alexis K. Potemkin,Mary M. Pollock,Sara Mc Clellan,Melissa Laron,Tamara Owens,Philip Costello,Philip Costello,Francine L. Jacobson,Andetta R. Hunsaker,Paul W. Spirn,Beatrice Trotman-Bickenson,Voula E. Christopoulos,Ivana K. Kazda,Regina C. MacDougall,Annmarie Walsh,Richard D. Nawfel,Robert L. Berger,Pearl Chan,Mark Delano,Jeffrey Geiger,Carl Krinopol,Ann D. McGinnis,Angela M. McLaughlin,Raymond Weatherby,Glenn A. Tung,Martha Maineiro,Lila Camara,Cindy Cobb,Susan Foley,Elizabeth Morrell,Diane Romano,Darlene Guillette,Wendy Smith,Joseph Aisner,Murray Backer,Mark Bramwitt,Victor De Caravalho,Robert Epstein,Peggy Joyce,John E. Langenfeld,Ann Reinert,Kevin DeMarco,Stuart Lutzker,Rita Musanti,Steven Shiff,Tammy Wolfsohn,Colleen Hudak,Andrea Hugill,Marisol Furlong,Elayne Weslowsky,Sharon Carmen,Denise L. Foster,Kenneth Hansen,Bernadette Pennetta,Linda V. White,Robert Tokarz,Maryann Trotta,Ana Birofka,Claudia J. Kasales,Petra J. Lewis,John B. Weaver,Suzanne B. Lenz,Angelica C. Barrett,Raymond Dauphinais,Jennifer R. Heinz,Matthew K. Siemionko,Ami Lyn Taplin,Lisa Scott Wasson,Linda DeAlmeida,Sharon Longacre,Katherine Meagher,Carol M. Moser,John K. Lawlor,Casey O'Quinn,Nancy E. Krieger Black,Heather L. Bradley,Jill K. Bronson,Timothy Cosgrove,Mark K. Haron,Donna King,Pamela M. Mazuerk,Neil F. O'Donnell,Daniel J. Pluta,Terry J. Sackett,Ginette D. Turgeon,Henry Albano,Courtney Bell,Jerry Bergen,Gail Bizer,Nicole M. Carmichael,Crista Cimis,Stephanie Davis,Tony DeAngelis,Gail Fellows,Charlie Fenton,Joy Ferola,Nancy Gankiewicz,Dorothy Hastings,Chris Howell,Mary E. Johnson,Mary Krisk,Heather Lancor,Christie Leary,Maurice LeBlanc,Adam Leming,Mandie Leming,Dawn Mead,Michael Milacek,Jamie Mood,Heidi Nordstrom,Carolyn Palazzolo,Jeremy Pierce,Richard P. Remitz,Jessica Rider,Kathleen A. Robbins,Brenda Sleasman,Jason Spaulding,Cam Vashel,Amie Welch,Linda White,Mark Whitty,Angela M. Williams,Andrew Karellas,Leeta Grayson,Carlotta McCalister-Cross,Sherri Mesquita,Anne Nguyen,Laura N. Myers,Eric Deaton,Sharon Maxfield,Kevin Thomas,Pamela Allen,Denise Brooks,Carla Chadwell,Elizabeth Couch,Amanda Devore,Rubenia Flores,Melba Francis,Sarah Landes,Jacinta Mattingly,Margaret Oechsli,Bethany Pitino,Shawn Sams,Olga Soukhanova,Priscilla Bland,Sheron Bube,Tricia Hoffa,Becky McElsain,Demetria Johnson,Cathy Francow,Stephenie Johnson,Pam Senn,Karen M. Horton,Leo P. Lawler,Lynne Bradford,Gale Christensen,Janet Bishop,Laura Motley,Beborah Robertson,Robin Stewart,Carmen Guzman,Heather Bishop Blake,Holly Bradford,Jenna Bradford,James Burner,Jennifer Kasecamp,Jennifer Bishop Kaufmann,Daniel Kimball,Zipporah Lewis,Sheila Moesinger,Susan Walsh,Karen Taylor,Rex C. Yung,Mingying Zeng,Greg Gambill,Sarah Merrill,Mahadevappa Mahesh,Elizabeth Johnson,Howard I. Jolies,Ronald S. Kuzo,Richard L. Morin,Reza Abaya,Deborah M. Chewar,Patricia Shwarts,Susan Allen,Shalonda Manning,Mary Adams Zafar Awan,Jacksonville,Fla Lisa Beagle,Dcanna Cape,Tanya Zeiger,Laurie Amendolare,Noel Bahr,Minnetta Belyea,Tara Berg,Mia Burkhard,Lisa Cottrell,Katherine BeAngelis,Melanie Bvorak,L. Heather,Kelly Hatton,Sharon Jacoby,Valene Kennedy,Kathleen Krach,Melissa Laughren,Cindy Lavergne,Marsha Lawrence,Jeannette Lynch,Amber McDonald,Felix Mestas,Julie Moody,Carrie O'Brien,Janice Pitts,Brenda Polding,Lindsay Richardson,Karen Robinson,Amy Warren,Holly Washburn,Erik Wilson,Luis Zagarra,Karen Mathews Batton,David Chellini,Kathleen DeWitt,Darlene R. Fleming,Christi Newton-Foster,Renee MacDonald,Jennifer Ott,Julie Peterson,Michele Sallas,Michael Teepe,Rachel Black Thomas,Kathy Torrence,Jodi Hildestad,Thomas E. Hartman,James R. Jett,Cynthia H. McCollough,Bavid E. Midthun,Boleyn R. Andrist,Nancy E. Hanson,Connie L. Sathre,Laura B. Schroeder,Jacqueline R. Sheeran,Lana C. Walters,Cynthia L. Andrist,Aaron O. Bungum,Cathy L. Bornhorst,Bawn M. Beno,Tami Krpata,Ann M. Lambrecht,Christine M. McKey,Belores K. Prudoehl,Helena R. Richter,Alan Brisendine,Tricia Adrales-Bentz,Krystal Arnold,Brad Benjamin,Andrew Bodd,John Keller,Tamara Saunders,Paola Spicker,Susan Shannon,Laura Bailey,Hanna Comer,Joy Espiritu,Stephanie Helwi,Brandy Mack-Pipkin,Melvin Tockman,Beth Evans,Nina Wadhwa,Natalie Baptiste,Courtney Eysmans,Naima Vera-Gonzalez,Lori Hamm,Veenu Harjani,Anna Sear,Susan Blackwell,Adys Fernandez,Edwin G. Williams,Kenneth A. Coleman,Jay Afiat,Lori Kirchoff,Rob Bowman,Barry H. Cohen,Nicole Fields,Richard Guzman,Celeste Monje,Winston Sterling,Loretta Thorpe,Kevin T. White,Buddy Williams,Erin Nekervis,Andrea Franco,Lena Glick,Marcello Grigolo,Yassminda Harts,Arthur Migo,Kelli P. Rockwell,Adam C. Stein,Ryan Weyls,Eric J. Berns,Michelle T. Biringer,Angela Del Pino,Peter Dubbs,Glenna M. Fehrmann,Alan Lee Goodwin,Loretta Granger,Julie Haglage,Jenny Hirschy,Mollie King,Jody Wietharn Kristopher,Nicole Matetic Mac,George Mahoney,Armen Markarian,Martha Ramirez,Michael A. Taylor,Kelli M. West,Michael A. Sullivan,Charles C. Matthews,Jerome Jones,Aura Cole,Pamela Dow,Jacqueline Fearon,Brent Fodera,Barbara Ginther,Rachel L. McCall,Shannon Williams,Serelda Young,Cristine Juul,Angele LaFleur,Katherine Lohmann,Lisa Pineda,Alison Schmidt,Shannon Wright,Sheila Greenup,Kelly McNulty,Stephanie Pawlak,Heather Porter,Teresa Lanning,Debra Loria,Albert J. Cook,Jo Ann Hall Sky,Anthony Boulos,Pritha Dalal,Ben Dickstein,Alice DuChateau,Catherine Engartner,Dianalyn M. Evans,James P. Evans,Kaylene Evans,Mary Gemmel,Sarah Hallsky,Phil Hoffman,Craig Hritz,Lorraine Kerchum,Mallory Kolich,Mark Kolich,Melody Kolich,Neha Kumar,Judith Lobaugh,Cheryl Love,Dayna Love,Melissa Love,Maria Marchese,Deana Nelson,Carrie Petkus,Marcella Petruzzi,Cristina Raver,Erin Schuler,Patricia Schuler,David Schultz,Robert Kobistek,Jacqueline Jackson,Johanna Ziegler,Jennifer Fleischer,Linda L. Welch,Marian Acerra,Beverly Brittain,Lisa Conklin,Cindy Cyphert,Brenda Delfosse,Leanne Franceshelli,Joan Fuller,Donna Garland,Peggy J. Gocala,Mauren Grunenwald,Diane Kowalik,Sharon L. Kurjan,Patricia Lavernick,Julie Maderitz,Renee Metz,Roberta Quinn,Marlene Semansky,Stacy E. Smith,Amy St.Claire,Pamela Taybus,Diana Wisler,Karen Zubena,Catherine Duda,Polly Kay,Patty Trapnell,Maria Vlachou,Brandon B. Bigby,Audrey Gallego,Gregg Hamm,Jill Spivak,Maisha Pollard,Eng Brown,Olivia Campa,Barbara L. Carter,Sonya Clark,Marvin Flores,Judy Ho,Tracy Lee,Barbara Lewis,Janie McMahon,Lea Momongan,Julie Ngo,Adele Perryman,Nicole Rivas,Christina Romo,Kanistha Sookpisal,Lily Stone,Barbara Voight,Carleaner Williams,Kellyn Adams,Phi Do,Kerry Engber,Leslie Henry,Michael Khalili,Sandy Morales,Chelsea O'Carroll,Jade Quijano,Shiva Borgheian,Roger Inatomi,Alfonso Lorenzo,Dinah Lorenzo,Glen K. Nyborg,Vinis Salazar,Michael Woo,Paige Beck,Paula R. Beerman,Jean Jacobsen,Kathleen Voight,Erich Allman,Sabrina Chen,Cristina Farkas,Isabelle Forter,Paul Marcus,Lonna Matthews,Roxana Phillips,Jessica Silva-Gietzen,Erica Sturgeon,Gina Varner,Brian Mullen,William Stanford,Eric A. Hoffman,Kim Sprenger,Andrea Chapman,Kaylene Crawford,Jacquie Marietta,Leslie Kmetty,Jackie Meier,Phyllis Pirotte,Laurie Rathmell,Melissa Hudson,Jered Sieren,Paul Cronin,Barry H. Gross,Aine Marie Kelly,Smita Patel,Perry G. Pernicano,Lisa A. Holloway,Gwen Chalom,Eric Henricks,Jim Pool,Diane Shepherd,Deanna Zapolski,Mitch Goodsitt,Hope Hooks,Warren B. Gefter,D. Lynn Werner,Catherine E. Smith,Byung Choi,Joon K. Lee,Christine Holland,Jacqueline Matuza,Hilary C. Nosker,William Russell,Scott Cupp,Michael J. O'Shea,Reginald F. Munden,Melissa Cates,Eric Sanchez,Michelle Aganon-Acheta,Michael Black,Dalphany Blalock,Cynthia A. Brown,Hattie Cromwell,Joel Dunnington,Jeremy J. Erasmus,Gregory W. Gladish,Sanjay Gupta,Michelle Wann Haynes,Thomas Hensley,Revathy B. Iyer,John E. Madewell,Tamim Malbari,Edith M. Marom,Rodolfo C. Morice,Sujaya Rao,Bradley S. Sabloff,Natalie F. Scully,Sangeeta Tekchandani,Mylene T. Truong,Danielle Wicks,William R. Geiser,Jerry L. Montague,Minesh Patel,Tonda Robinson,Edwin F. Donnelly,Elizabeth Thielke,Allie M. Bell,David R. Pickens,Walter Allen Bowman,Tina Herron,Dawn Shone,Brian Chin,M. Y. M. Chen,Lisa Harmon,Lisa B. Hinshaw,Carolyn Nelson,Donna Biracree,Denise Boyles,Anne Burrough,Amanda C. Davis,Elliott Drake,Eileen Frost,Ashley B. Long,Elaine Bowman,Susanna N. Dyer +1336 more
TL;DR: The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography with chest radiography in the screening of older current and former heavy smokers for early detection of lung cancer.
Journal ArticleDOI
Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies
Gregory L. Beatty,Andrew R. Haas,Marcela V. Maus,Drew A. Torigian,Michael C. Soulen,Gabriela Plesa,Anne Chew,Yangbing Zhao,Bruce L. Levine,Steven M. Albelda,Michael Kalos,Carl H. June +11 more
TL;DR: Findings support the development of mRNA CAR-based strategies for carcinoma and other solid tumors by showing the potential of using mRNA-engineered T cells to evaluate, in a controlled manner, potential off-tumor on-target toxicities and showing that short-lived CAR T cells can induce epitope spreading and mediate antitumor activity in patients with advanced cancer.
Journal ArticleDOI
A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma
Gregory L. Beatty,Drew A. Torigian,E. Gabriela Chiorean,Babak Saboury,Abass Alavi,Andrea B. Troxel,Weijing Sun,Ursina R. Teitelbaum,Robert H. Vonderheide,Peter J. O'Dwyer +9 more
TL;DR: CP-870,893 in combination with gemcitabine was well-tolerated and associated with antitumor activity in patients with PDA, and changes in FDG uptake detected on PET/CT imaging provide insight into therapeutic benefit.
Journal ArticleDOI
Combined MTOR and autophagy inhibition: Phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma
Reshma Rangwala,Yunyoung C. Chang,Janice Hu,Kenneth M. Algazy,Tracey L. Evans,Leslie A. Fecher,Lynn M. Schuchter,Drew A. Torigian,Jeffrey T. Panosian,Andrea B. Troxel,Kay See Tan,Daniel F. Heitjan,Angela DeMichele,David J. Vaughn,Maryann Redlinger,Abass Alavi,Jonathon Kaiser,Laura Pontiggia,Lisa E. Davis,Peter J. O'Dwyer,Ravi K. Amaravadi +20 more
TL;DR: TEM and HCQ is safe and tolerable, modulates autophagy in patients, and has significant antitumor activity, according to this phase 1 dose-escalation study.