F
Federico E. Rey
Researcher at University of Wisconsin-Madison
Publications - 102
Citations - 23453
Federico E. Rey is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Gut flora & Microbiome. The author has an hindex of 39, co-authored 80 publications receiving 18673 citations. Previous affiliations of Federico E. Rey include Henry Ford Health System & University of California, Los Angeles.
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Journal ArticleDOI
Human gut microbiome viewed across age and geography
Tanya Yatsunenko,Federico E. Rey,Mark J. Manary,Mark J. Manary,Indi Trehan,Indi Trehan,Maria Gloria Dominguez-Bello,Monica Contreras,Magda Magris,Glida Hidalgo,Robert N. Baldassano,Andrey P. Anokhin,Andrew C. Heath,Barbara B. Warner,Jens Reeder,Justin Kuczynski,J. Gregory Caporaso,Catherine A. Lozupone,Christian L. Lauber,Jose C. Clemente,Dan Knights,Rob Knight,Jeffrey I. Gordon +22 more
TL;DR: The need to consider the microbiome when evaluating human development, nutritional needs, physiological variations and the impact of westernization is underscored, as distinctive features of the functional maturation of the gut microbiome are evident in early infancy as well as adulthood.
Journal ArticleDOI
Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
Vanessa K. Ridaura,Jeremiah J. Faith,Federico E. Rey,Jiye Cheng,Alexis E. Duncan,Andrew L. Kau,Nicholas W. Griffin,Vincent Lombard,Bernard Henrissat,Bernard Henrissat,James R. Bain,Michael J. Muehlbauer,Olga Ilkayeva,Clay F. Semenkovich,Katsuhiko Funai,David K. Hayashi,Barbara J. Lyle,Margaret C. Martini,Luke K. Ursell,Jose C. Clemente,Will Van Treuren,William A. Walters,Rob Knight,Rob Knight,Christopher B. Newgard,Andrew C. Heath,Jeffrey I. Gordon +26 more
TL;DR: The results reveal that transmissible and modifiable interactions between diet and microbiota influence host biology and that adiposity is transmissible from human to mouse and that it was associated with changes in serum levels of branched-chain amino acids.
Journal ArticleDOI
The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice
Peter J. Turnbaugh,Vanessa K. Ridaura,Jeremiah J. Faith,Federico E. Rey,Rob Knight,Jeffrey I. Gordon +5 more
TL;DR: A translational medicine pipeline is described where human gut microbial communities and diets are re-created in gnotobiotic mice and the impact on microbe and host is defined using metagenomics, creating a well-defined, representative animal model of the human gut ecosystem.
Journal ArticleDOI
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
Buck S. Samuel,Abdullah Shaito,Toshiyuki Motoike,Federico E. Rey,Fredrik Bäckhed,Fredrik Bäckhed,Jill K. Manchester,Robert E. Hammer,S. Clay Williams,Jan R. Crowley,Masashi Yanagisawa,Jeffrey I. Gordon +11 more
TL;DR: Functional genomic, biochemical, and physiologic studies reveal that Gpr41 is a regulator of host energy balance through effects that are dependent upon the gut microbiota.
Journal ArticleDOI
Gut microbiome alterations in Alzheimer's disease.
Nicholas M. Vogt,Robert L. Kerby,Kimberly A. Dill-McFarland,Sandra Harding,Andrew P. Merluzzi,Sterling C. Johnson,Cynthia M. Carlsson,Sanjay Asthana,Henrik Zetterberg,Kaj Blennow,Kaj Blennow,Barbara B. Bendlin,Federico E. Rey +12 more
TL;DR: The gut microbiome of AD participants has decreased microbial diversity and is compositionally distinct from control age- and sex-matched individuals, which adds AD to the growing list of diseases associated with gut microbial alterations, as well as suggest that gut bacterial communities may be a target for therapeutic intervention.