H
Hirokazu Nagawa
Researcher at University of Tokyo
Publications - 401
Citations - 13236
Hirokazu Nagawa is an academic researcher from University of Tokyo. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 57, co-authored 401 publications receiving 12477 citations.
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CD11b-mediated migratory property of peripheral blood B cells
Kazushige Kawai,Nelson H. Tsuno,Mika Matsuhashi,Joji Kitayama,Takuya Osada,Jun Yamada,Takeshi Tsuchiya,Satomi Yoneyama,Toshiaki Watanabe,Koki Takahashi,Hirokazu Nagawa +10 more
TL;DR: Memory B cells express CD11b and, in contrast with naive B cells, have high migratory ability and plays an essential role in the homing process of memory cells.
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Epigallocatechin gallate affects human dendritic cell differentiation and maturation
Satomi Yoneyama,Kazushige Kawai,Nelson H. Tsuno,Yurai Okaji,Masahiro Asakage,Takeshi Tsuchiya,Jun Yamada,Eiji Sunami,Takuya Osada,Joji Kitayama,Koki Takahashi,Hirokazu Nagawa +11 more
TL;DR: Investigation of the effect of EGCG on human monocyte-derived DCs (MODCs) and on the T-cell-mediated immune response induces immunosuppressive alterations on human MODCs, both by induction of apoptosis and suppression of cell surface molecules and antigen presentation.
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Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants.
TL;DR: The cellular response to exogenous long-chain PUFAs is modified during the course of malignant transformation, and EPA and DHA appear to have specific inhibitory effects on cancer cells and may thus enhance the host defense against colon cancer.
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Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells
TL;DR: It is concluded that adiponectin supports cell survival in glucose deprivation through enhancement of the autophagic machinery by AMPKα and PPARα activation and IGF‐1/PI3k/Akt/mTOR pathway inhibition.
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Intraoperative Blood Loss is a Critical Risk Factor for Peritoneal Recurrence After Curative Resection of Advanced Gastric Cancer
TL;DR: Intraoperative blood loss in curative gastrectomy for advanced gastric cancer may have a specific association with the development of peritoneal recurrence, and surgeons must remember that clean and dry surgery may lessen not only 30-day mortality and morbidity but long-term peritoneAL recurrence in Gastric cancer.