H
Hirokazu Nagawa
Researcher at University of Tokyo
Publications - 401
Citations - 13236
Hirokazu Nagawa is an academic researcher from University of Tokyo. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 57, co-authored 401 publications receiving 12477 citations.
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Enhanced Expression of Leptin and Leptin Receptor (OB-R) in Human Breast Cancer
TL;DR: Leptin may have a promoting effect on the carcinogenesis and metastasis of breast cancer, possibly in an autocrine manner and functional inhibition of leptin may be effective for the prevention and treatment of Breast cancer.
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Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells
Kazuhito Sasaki,Nelson H. Tsuno,Eiji Sunami,Giichiro Tsurita,Kazushige Kawai,Yurai Okaji,Takeshi Nishikawa,Yasutaka Shuno,Kumiko Hongo,Masaya Hiyoshi,Manabu Kaneko,Joji Kitayama,Koki Takahashi,Hirokazu Nagawa +13 more
TL;DR: The findings suggest that the combination therapy with CQ should be a novel therapeutic modality to improve efficacy of 5-FU-based chemotherapy, possibly by inhibiting autophagy-dependent resistance to chemotherapy.
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Risk Factors for Anastomotic Leakage after Surgery for Colorectal Cancer: Results of Prospective Surveillance
TL;DR: Preoperative steroid use, longer duration of operation, and contamination of the operative field were independent risk factors for developing clinical anastomotic leakage after elective resection for colorectal cancer.
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Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study.
Takashi Shimoyama,Koji Sawada,Nobuo Hiwatashi,Toshio Sawada,Kei Matsueda,Akihiro Munakata,Hitoshi Asakura,Takao Tanaka,Reiji Kasukawa,Ken Kimura,Yasuo Suzuki,Yukio Nagamachi,Tetsuichiro Muto,Hirokazu Nagawa,Bunei Iizuka,Shozo Baba,Masaru Nasu,Tatsuji Kataoka,Nobuhito Kashiwagi,Abby R. Saniabadi +19 more
TL;DR: Based on the results, it is believed that in patients with active severe UC, patients who are refractory to conventional drugs, granulocyte and monocyte adsorption apheresis is a useful adjunct to conventional therapy.
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Elective colon and rectal surgery differ in risk factors for wound infection: results of prospective surveillance.
TL;DR: Colon and rectal surgeries differ with regard to incidence and risk factors for developing incisional SSI, and SSI surveillance for such surgeries should be performed separately, as this should lead to more efficient identification of risk factors and a reduction in SSI.