I. Vermes

TL;DR: The smallest model of the blood-brain barrier yet is presented, using a microfluidic chip, and the immortalized human brain endothelial cell line hCMEC/D3, which is very well suited to study barrier function and evaluate drug passage to finally gain more insight into the treatment of neurodegenerative diseases.

TL;DR: This article uses a planar curved microchannel structure in PDMS to spatially order two types of myeloid leukemic cells, enabling deterministic single cell encapsulation in picolitre drops and confirms that > 90% of the cells remain viable.

TL;DR: It is shown how microfluidic technology can be employed to provide a mechanistic insight into cell physiology by adding inhibitory drugs to analyze the alignment of actin filaments in endothelial cells in response to shear stress.

TL;DR: A microfluidic chip for fast and label-free electrical impedance based detection of cells in droplets and the proposed method provides the first step towards additional information regarding the encapsulated cells (e.g., size, number, morphology).

TL;DR: The development and full characterization of a microfluidic chip for electrofusion of human peripheral blood B‐cells and mouse myeloma (NS‐1) cells to generate hybridomas is described and provides valuable leads to improve the current electrofusions protocols for the production of human antibodies for diagnostic and therapeutic applications.