I
Izabela Koryga
Researcher at National University of Ireland, Galway
Publications - 3
Citations - 1534
Izabela Koryga is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Unfolded protein response & Integrated stress response. The author has an hindex of 2, co-authored 3 publications receiving 1003 citations.
Papers
More filters
Journal ArticleDOI
The integrated stress response.
Karolina Pakos-Zebrucka,Izabela Koryga,Katarzyna Mnich,Mila Ljujic,Afshin Samali,Adrienne M. Gorman +5 more
TL;DR: Current understanding of the ISR signaling is reviewed and how it regulates cell fate under diverse types of stress is reviewed.
Journal ArticleDOI
A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy
TL;DR: Of particular interest is the transcriptional upregulation of the autophagy receptor genes SQSTM1/p62, NBR1 and BNIP3L/NIX in response to ER stress and it is shown that the inhibition of the UPR transmembrane receptors, PERK and IRE1, abrogates this upregulation.
Journal ArticleDOI
The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner.
Katarzyna Mnich,Izabela Koryga,Karolina Pakos-Zebrucka,Melissa Thomas,Susan E. Logue,Leif A. Eriksson,Adrienne M. Gorman,Afshin Samali +7 more
TL;DR: In this article, the authors investigated whether a protein complex containing ATG5 and Fas-associated death domain (FADD) facilitated caspase-8 activation and cell death in response to endoplasmic reticulum (ER) stress.