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Afshin Samali

Researcher at National University of Ireland, Galway

Publications -  206
Citations -  27237

Afshin Samali is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Unfolded protein response & Apoptosis. The author has an hindex of 64, co-authored 198 publications receiving 23836 citations. Previous affiliations of Afshin Samali include Karolinska Institutet & Pompeu Fabra University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mediators of endoplasmic reticulum stress-induced apoptosis.

TL;DR: The role of the molecules that are activated during the UPR is examined in order to identify the molecular switch from the adaptive phase to apoptosis and how the activation of these molecules leads to the commitment of death and the mechanisms that are responsible for the final demise of the cell.
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The integrated stress response.

TL;DR: Current understanding of the ISR signaling is reviewed and how it regulates cell fate under diverse types of stress is reviewed.
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Triggering and modulation of apoptosis by oxidative stress.

TL;DR: This review will address some of the current paradigms for oxidative stress and apoptosis, and discuss the potential mechanisms by which oxidants can modulate the apoptotic pathway.
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Cellular Stress Responses: Cell Survival and Cell Death

TL;DR: The implications of cellular stress responses to human physiology and diseases are manifold and will be discussed in this review in the context of some major world health issues such as diabetes, Parkinson's disease, myocardial infarction, and cancer.