Juergen Lademann

TL;DR: It was found that the nanoparticles penetrate much deeper into the hair follicles than the dye in the non-particle form, if a massage had been applied and without massage, similar results were obtained for both formulations.

TL;DR: The structure of porcine ear skin, including hair follicles, was studied qualitatively and quantitatively in comparison with human skin in studies of percutaneous penetration.

TL;DR: Investigation of the suitability of nanoparticles in transcutaneous vaccine administration found a high density of Langerhans cells around hair follicles that, when sorted, readily internalized all size particles, but not 750 or 1,500 nm nanoparticles, may be efficiently used.

TL;DR: The tape stripping method in its standardized form is well-suited to determine the dermatopharmacokinetics of topically applied substances and is used, e.g., for the determination of the homogeneity of the distribution and the ex vivo determination of a universal sun protection factor characterizing the efficacy of sunscreens.

TL;DR: By varying the particle size, different sites within the porcine hair follicle can be targeted selectively, and the situation can be expected to be similar due to a similar size ratio of the hair follicles.