W
Wolfram Sterry
Researcher at Charité
Publications - 302
Citations - 18200
Wolfram Sterry is an academic researcher from Charité. The author has contributed to research in topics: Psoriasis & Human skin. The author has an hindex of 71, co-authored 302 publications receiving 16719 citations.
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Journal ArticleDOI
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes : a potential role in psoriasis
Kerstin Wolk,Ellen Witte,Elizabeth Wallace,Wolf-Dietrich Döcke,Stefanie Kunz,Khusru Asadullah,Hans-Dieter Volk,Wolfram Sterry,Robert Sabat +8 more
TL;DR: It is demonstrated that IL‐22, in contrast to its relative IFN‐γ, regulates the expression of only a few genes in keratinocytes, which may be important in the innate immunity and reorganization of epithelia.
Journal ArticleDOI
Nanoparticles--an efficient carrier for drug delivery into the hair follicles.
Juergen Lademann,Heike Richter,A. Teichmann,Nina Otberg,Ulrike Blume-Peytavi,Javiana Luengo,Javiana Luengo,Barbara Weiss,Ulrich F. Schaefer,Claus-Michael Lehr,Roger Wepf,Wolfram Sterry +11 more
TL;DR: It was found that the nanoparticles penetrate much deeper into the hair follicles than the dye in the non-particle form, if a massage had been applied and without massage, similar results were obtained for both formulations.
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Immunopathogenesis of psoriasis
Robert Sabat,Sandra Philipp,Conny Höflich,Stefanie Kreutzer,Elizabeth Wallace,Khusru Asadullah,Hans-Dieter Volk,Wolfram Sterry,Kerstin Wolk +8 more
TL;DR: It is postulated that the pathogenesis of psoriasis consists of distinct subsequent stages, in each of them different cell types playing a dominant role, which helps to explain the varied effectiveness of the currently tested immune modulating therapies and may enable the prediction of the success of future therapies.
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Porcine ear skin: an in vitro model for human skin
Ute Jacobi,Marco Kaiser,Rani Toll,Susanne Mangelsdorf,Heike Audring,Nina Otberg,Wolfram Sterry,Juergen Lademann +7 more
TL;DR: The structure of porcine ear skin, including hair follicles, was studied qualitatively and quantitatively in comparison with human skin in studies of percutaneous penetration.
Journal ArticleDOI
IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not
Kerstin Wolk,Harald S. Haugen,Wenfeng Xu,Ellen Witte,Kim Waggie,Monica Anderson,Elmar vom Baur,Katrin Witte,Katarzyna Warszawska,Sandra Philipp,Caroline Johnson-Leger,Hans-Dieter Volk,Wolfram Sterry,Robert Sabat +13 more
TL;DR: It is suggested that different cytokines are players in the psoriasis pathogenesis although only the IL-10 family members IL-22 and IL-20 directly cause the characteristic epidermal alterations.