K
Keijo Viiri
Researcher at University of Tampere
Publications - 38
Citations - 1910
Keijo Viiri is an academic researcher from University of Tampere. The author has contributed to research in topics: Corepressor & Transcytosis. The author has an hindex of 16, co-authored 35 publications receiving 1682 citations. Previous affiliations of Keijo Viiri include University College London & University of Oulu.
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Journal ArticleDOI
Glacial history and colonization of Europe by the blue tit Parus caeruleus
TL;DR: It is suggested that after the last Ice Ages, the blue tit subspecies have colonized Europe from two different southern refuges following previously proposed general recolonization routes from the Balkans to northern and Central Europe, and from the Iberian Peninsula north- and eastwards.
Journal ArticleDOI
Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2
Aditi Kanhere,Keijo Viiri,Carla C. Araújo,Jane Rasaiyaah,Russell D. Bouwman,Warren A. Whyte,C. Filipe Pereira,Emily Brookes,Kimberly Walker,George W. Bell,Ana Pombo,Amanda G. Fisher,Richard A. Young,Richard G. Jenner +13 more
TL;DR: A class of short RNAs, approximately 50-200 nucleotides in length, transcribed from the 5' end of polycomb target genes in primary T cells and embryonic stem cells are identified and it is proposed that shortRNAs play a role in the association of PRC2 with its target genes.
Journal ArticleDOI
The interaction of PRC2 with RNA or chromatin is mutually antagonistic.
Manuel Beltran,Christopher M. Yates,Lenka Skalska,Marcus Dawson,Filipa P. Reis,Keijo Viiri,Cynthia L. Fisher,Christopher R. Sibley,Benjamin M. Foster,Till Bartke,Jernej Ule,Richard G. Jenner +11 more
TL;DR: It is shown here that PRC2 binds nascent RNA at essentially all active genes, and that mutual antagonism between RNA and chromatin underlies the pattern ofPRC2 chromatin association across the genome.
Journal ArticleDOI
DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides.
Keijo Viiri,Janne Jänis,Trevor Siggers,Taisto Y. K. Heinonen,Jarkko Valjakka,Martha L. Bulyk,Martha L. Bulyk,Markku Mäki,Olli Lohi +8 more
TL;DR: The results suggest that SAP30L and SAP30 play active roles in recruitment of deacetylating enzymes to nucleosomes, and mediate key protein-protein and protein-DNA interactions involved in chromatin remodeling and transcription.
Journal ArticleDOI
Safety and efficacy of AMG 714 in patients with type 2 refractory coeliac disease: a phase 2a, randomised, double-blind, placebo-controlled, parallel-group study
Christophe Cellier,Gerd Bouma,Tom van Gils,Sherine Khater,Georgia Malamut,Laura Crespo,Pekka Collin,Peter H.R. Green,Sheila E. Crowe,Wayne Tsuji,Eric Butz,Nadine Cerf-Bensussan,Elizabeth Macintyre,Jane R. Parnes,Francisco Leon,Olivier Hermine,Chris J. J. Mulder,Bana Jabri,Joseph A. Murray,Anthony J. DiMarino,Ciaran P. Kelly,Valerie Byrnes,David S Sanders,Knut E.A. Lundin,Michael Schumann,Hetty J. Bontkes,Bertrand Meresse,Garbiñe Roy Ariño,Govind Bhagat,Keijo Viiri,Samuli Rounioja,Jack D. Bui,Raquel Perez Maseda,Carlota García-Hoz,Amélie Trinquand,George Vlad,Marios Hadjivassiliou,Michel Azizi,Anne Blanchard,Beth Llewellyn,Ashleigh Palmer,Ralph Raymond +41 more
TL;DR: The effects of AMG 714, an anti-IL-15 monoclonal antibody, on the activity and symptoms of refractory coeliac disease type 2 and atypical intraepithelial lymphocytes were investigated.