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Laura A. Hug

Researcher at University of Waterloo

Publications -  70
Citations -  8324

Laura A. Hug is an academic researcher from University of Waterloo. The author has contributed to research in topics: Metagenomics & Genome. The author has an hindex of 30, co-authored 61 publications receiving 6802 citations. Previous affiliations of Laura A. Hug include University of California, Berkeley & University of Toronto.

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Unusual biology across a group comprising more than 15% of domain Bacteria

TL;DR: This work reconstructed 8 complete and 789 draft genomes from bacteria representing >35 phyla and documented features that consistently distinguish these organisms from other bacteria, infer that this group, which may comprise >15% of the bacterial domain, has shared evolutionary history, and describe it as the candidate phyla radiation (CPR).
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Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system

TL;DR: Terabase-scale cultivation-independent metagenomics is applied to aquifer sediments and groundwater and 2,540 draft-quality, near-complete and complete strain-resolved genomes are reconstructed, finding that few organisms within the community can conduct multiple sequential redox transformations.
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Genomic Expansion of Domain Archaea Highlights Roles for Organisms from New Phyla in Anaerobic Carbon Cycling

TL;DR: This study sequenced DNA from complex sediment and planktonic consortia from an aquifer adjacent to the Colorado River and reconstructed the first complete genomes for Archaea using cultivation-independent methods, which dramatically expand genomic sampling of the domain Archaea and clarify taxonomic designations within a major superphylum.
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Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic “supergroups”

TL;DR: A phylogenomic analysis of a dataset of 143 proteins and 48 taxa indicates that Excavata forms a monophyletic suprakingdom-level group that is one of the 3 primary divisions within eukaryotes, along with unikonts and a megagroup of Archaeplastida, Rhizaria, and the chromalveolate lineages.