L
Lindolfo da Silva Meirelles
Researcher at Universidade Luterana do Brasil
Publications - 29
Citations - 5580
Lindolfo da Silva Meirelles is an academic researcher from Universidade Luterana do Brasil. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 13, co-authored 27 publications receiving 5157 citations. Previous affiliations of Lindolfo da Silva Meirelles include Universidade Federal do Rio Grande do Sul & University of São Paulo.
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Journal ArticleDOI
Mesenchymal stem cells reside in virtually all post-natal organs and tissues
TL;DR: The results suggest that the distribution of MSCs throughout the post-natal organism is related to their existence in a perivascular niche, which has implications for understanding MSC biology, and for clinical and pharmacological purposes.
Journal ArticleDOI
Mechanisms involved in the therapeutic properties of mesenchymal stem cells
Lindolfo da Silva Meirelles,Aparecida Maria Fontes,Dimas Tadeu Covas,Dimas Tadeu Covas,Arnold I. Caplan +4 more
TL;DR: Some of the molecules involved in the paracrine effects of MSCs are identified with a perspective that these cells intrinsically belong to a perivascular niche in vivo, and how this knowledge could be advantageously used in clinical applications is discussed.
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In search of the in vivo identity of mesenchymal stem cells
TL;DR: This model proposes that MSCs stabilize blood vessels and contribute to tissue and immune system homeostasis under physiological conditions and assume a more active role in the repair of focal tissue injury and provides a basis for the rational design of additional in vivo therapeutic approaches.
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Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization.
TL;DR: The emergence of a defined methodology for the culture of mMSCs, as well as a comprehensive understanding of their biology, will make the development of cellular and genetic therapy protocols in murine models possible, and provide new perspectives in the field of adult stem cells research.
Journal ArticleDOI
MSC frequency correlates with blood vessel density in equine adipose tissue
Lindolfo da Silva Meirelles,Theodore T. Sand,Robert J. Harman,Donald P. Lennon,Arnold I. Caplan +4 more
TL;DR: To test the hypothesis that MSCs are associated with blood vessels by verifying if MSC frequency positively correlates with blood vessel density, samples from highly and poorly vascularized adipose tissue sites of two equine donors were collected and processed for histology and cell isolation.